Title:
ANTIBODY FOR PURE ISOLATION OF VASCULAR ENDOTHELIAL CELLS AND PREPARATION METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/040523
Kind Code:
A1
Abstract:
The present specification provides an antibody for pure isolation of vascular endothelial cells and a preparation method thereof, the antibody comprising: a heavy chain variable domain and a light chain variable domain which specifically bind to an extracellular matrix domain of PECAM1 having an amino acid sequence of SEQ ID NO: 1; or a heavy chain variable domain and a light chain variable domain which specifically bind to an extracellular matrix domain of CDH5 having an amino acid sequence of SEQ ID NO: 2.
Inventors:
YOON YOUNG SUP (KR)
LEE SHIN JEONG (KR)
SON DONG CHAN (KR)
LEE SHIN JEONG (KR)
SON DONG CHAN (KR)
Application Number:
PCT/KR2019/010571
Publication Date:
February 27, 2020
Filing Date:
August 20, 2019
Export Citation:
Assignee:
UNIV YONSEI IACF (KR)
International Classes:
C12N5/071; C07K16/28; G01N33/569; G01N35/00
Foreign References:
| US20090319033A1 | 2009-12-24 | |||
| US6087331A | 2000-07-11 | |||
| US5597725A | 1997-01-28 |
Other References:
MATSUBARA, T.: "Isolation and culture of rat retinal microvessel endothelial cells using magnetic beads coated with antibodies to PECAM-l", CURRENT EYE RESEARCH, 2000, XP002263445
"Isolation of Microvascular Endothelial Cells", BIO-PROTOCOL, vol. 8, no. 12, e2886, 20 June 2018 (2018-06-20)
"Isolation of Microvascular Endothelial Cells", BIO-PROTOCOL, vol. 8, no. 12, e2886, 20 June 2018 (2018-06-20)
Attorney, Agent or Firm:
INVENSYNC INTELLECTUAL PROPERTY GROUP (KR)
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