Title:
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MUSCLE DISEASES COMPRISING EXTRACT OF CODONOPSIS LANCEOLATA AS EFFECTIVE COMPONENT
Document Type and Number:
WIPO Patent Application WO/2020/040522
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition for preventing or treating muscle diseases, comprising an extract of Codonopsis lanceolata as an effective component. More specifically, the extract of Codonopsis lanceolata of the present invention alleviates reduction in muscle mass and muscle fiber cross sectional area due to muscle atrophy; reduces increased expressions of muscle RING-finger protein-1 (MuRF-1) and atrogin-1, involved in muscle protein breakdown; and increases the expression of phosphorylated mammalian target of rapamycin (p-mTOR) involved in muscle protein synthesis, and thus can be beneficially used in the prevention, alleviation, or treatment of muscle diseases.
Inventors:
JUNG WOO JAE (KR)
Application Number:
PCT/KR2019/010569
Publication Date:
February 27, 2020
Filing Date:
August 20, 2019
Export Citation:
Assignee:
JUNG WOO JAE (KR)
International Classes:
A61K36/344; A23K10/30; A23L33/105; A61K8/9789; A61P21/00; A61Q19/00
Foreign References:
| CN104784522A | 2015-07-22 | |||
| KR20100116919A | 2010-11-02 | |||
| KR20160138929A | 2016-12-06 | |||
| KR20110058556A | 2011-06-01 | |||
| US20030203057A1 | 2003-10-30 |
Other References:
LI, M. Z. ET AL.: "Effects of the Codonopsis lanceolata on skeletal muscle contractility in rats and forced swimming time in mice", JOURNAL OF MEDICAL SCIENCE YANBIAN UNIVERSITY, 2007
Attorney, Agent or Firm:
LEE, Won Hee (KR)
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