Title:
APPARATUS FOR GENERATING DISEASE-SPECIFIC RISK GENE MUTATION INFORMATION USING TIME-VARYING COVARIATE-BASED PRS MODEL, AND METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2023/080766
Kind Code:
A1
Abstract:
The present invention relates to a technology for performing disease-related gene mutation analysis using cohort data and generating disease-specific risk gene mutation information on the basis of the results. The objective of the present invention is to provide an apparatus for generating disease-specific risk gene mutation information using a time-varying covariate-based PRS model, and a method therefor, the apparatus being capable of, in assigning disease-specific genetic mutation correlation scores for each genetic mutation, providing relatively more accurate disease-specific genetic mutation correlation scores and risk gene mutation information for each genetic mutation by reflecting the influence of changes in the probability of disease occurrence over time.
Inventors:
KIM HO (KR)
KIM JUNG O (KR)
KIM JUNG EUN (KR)
YOON SANG HYUCK (KR)
LEE SOL (KR)
PARK SEUNG HWAN (KR)
KWON DO HYUNG (KR)
CHA JI HI (KR)
KIM NA YOUNG (KR)
KIM EUN GYO (KR)
PARK DA HYUN (KR)
AN JI MIN (KR)
SONG WOO JEUNG (KR)
KIM JUNG O (KR)
KIM JUNG EUN (KR)
YOON SANG HYUCK (KR)
LEE SOL (KR)
PARK SEUNG HWAN (KR)
KWON DO HYUNG (KR)
CHA JI HI (KR)
KIM NA YOUNG (KR)
KIM EUN GYO (KR)
PARK DA HYUN (KR)
AN JI MIN (KR)
SONG WOO JEUNG (KR)
Application Number:
PCT/KR2022/095109
Publication Date:
May 11, 2023
Filing Date:
June 27, 2022
Export Citation:
Assignee:
BASGENBIO CO LTD (KR)
International Classes:
G16B5/00; G06N3/04; G06N3/08; G16B20/20; G16B35/00; G16B40/20
Foreign References:
| KR20190138960A | 2019-12-17 | |||
| KR102223362B1 | 2021-03-05 | |||
| KR102063781B1 | 2020-01-08 | |||
| KR102087613B1 | 2020-03-11 | |||
| KR20190080832A | 2019-07-08 | |||
| KR20190000341A | 2019-01-02 | |||
| KR102389479B1 | 2022-04-25 |
Attorney, Agent or Firm:
SEO, Pyeong Gang (KR)
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