Title:
AROMATIC HETEROCYCLIC CYCLOHEXYL AMINOALKYL PIPERIDINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/032530
Kind Code:
A1
Abstract:
Provided are an aromatic heterocyclic cyclohexyl aminoalkyl piperidine derivative, a preparation method and a use thereof. Specifically, provided are a compound of formula (I), a stereoisomer thereof, a tautomer thereof or a pharmaceutically acceptable salt thereof, a preparation method therefor, and uses in activating the activities of a 5-HT1A receptor and dopamine D2 and D3 receptors and preparing a medicament for Parkinson's disease.
More Like This:
| WO/2013/144224 | ACETYLENIC MICROBIOCIDES |
| JP6576433 | Cyclopropyl condensed thiazine-2-amine compound as a β-secretase inhibitor and how to use it |
| JPWO2008007780 | Pentazienamide derivative |
Inventors:
WANG GUAN (CN)
HU ZHIJING (CN)
DU XINLI (CN)
GE YUQIANG (CN)
JIE PENG (CN)
MA LIANG (CN)
LI JIANQI (CN)
WAN ZEHONG (US)
HU ZHIJING (CN)
DU XINLI (CN)
GE YUQIANG (CN)
JIE PENG (CN)
MA LIANG (CN)
LI JIANQI (CN)
WAN ZEHONG (US)
Application Number:
PCT/CN2023/111410
Publication Date:
February 15, 2024
Filing Date:
August 07, 2023
Export Citation:
Assignee:
JIANGSU NHWA PHARMACEUTICAL CO LTD (CN)
SHANGHAI INST OF PHARMACEUTICAL INDUSTRY CO LTD (CN)
SHANGHAI INST OF PHARMACEUTICAL INDUSTRY CO LTD (CN)
International Classes:
C07D417/12; A61K31/39; A61K31/4427; A61P25/16; A61P25/22; A61P25/24; C07D211/06; C07D221/00; C07D277/60
Foreign References:
| US20050222175A1 | 2005-10-06 | |||
| CN113121417A | 2021-07-16 | |||
| US20200276196A1 | 2020-09-03 | |||
| CN1884262A | 2006-12-27 | |||
| US20090062261A1 | 2009-03-05 | |||
| CN101990535A | 2011-03-23 | |||
| CN1518547A | 2004-08-04 |
Download PDF: