ARRAYS COMPRISING PRE-LABELED BIOLOGICAL MOLECULES AND METHODS FOR MAKING AND USING THESE ARRAYS

Title:

ARRAYS COMPRISING PRE-LABELED BIOLOGICAL MOLECULES AND METHODS FOR MAKING AND USING THESE ARRAYS

Document Type and Number:

WIPO Patent Application WO2003020898

Kind Code:

A3

Abstract:

The invention provides arrays comprising a plurality of biological molecules, wherein each biological molecule is immobilized to a discrete and known spot on a substrate surface to form an array of biological molecules, and each biological molecule comprises a detectable label. The invention provides a multiplexed system for performing comparative genomic hybridization (CGH) using an array of the invention. The invention also provides methods of making and using these arrays, including a method of comparing copy numbers of unique nucleic acid sequences in a sample.

Inventors:

SHAH SHISHIR (US)
MOHAMMED MANSOOR (US)

Application Number:

PCT/US2002/027743

Publication Date:

November 20, 2003

Filing Date:

August 30, 2002

Export Citation:

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Assignee:

SPECTRAL GENOMICS INC (US)
SHAH SHISHIR (US)
MOHAMMED MANSOOR (US)

International Classes:

C12Q1/68; C12Q1/6837; (IPC1-7): C12Q1/68; C12M1/36; C12P19/34; G01N15/06

Foreign References:

US6025136A	2000-02-15
US5807522A	1998-09-15
US6037130A	2000-03-14
US6027890A	2000-02-22

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