ASSAY AND METHOD FOR DIAGNOSING AND TREATING ALZHEIMER'S DISEASE

Title:

ASSAY AND METHOD FOR DIAGNOSING AND TREATING ALZHEIMER'S DISEASE

Document Type and Number:

WIPO Patent Application WO2005076939

Kind Code:

A3

Abstract:

Methods and kits for diagnosing Alzheimer's disease and/or incipient Alzheimer's disease are disclosed. The methods and kits of the invention utilize a set of genes and their encoded proteins that are shown to be correlated with incipient Alzeimer's disease.

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Inventors:

LANDFIELD PHILIP W (US)
PORTER NADA M (US)
CHEN KUEY CHU (US)
GEDDES JAMES (US)
BLALOCK ERIC (US)

Application Number:

PCT/US2005/003668

Publication Date:

July 06, 2006

Filing Date:

February 09, 2005

Export Citation:

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Assignee:

UNIV KENTUCKY RES FOUND (US)
LANDFIELD PHILIP W (US)
PORTER NADA M (US)
CHEN KUEY CHU (US)
GEDDES JAMES (US)
BLALOCK ERIC (US)

International Classes:

C12Q1/68; C07H21/04

Foreign References:

US6720138B2

2004-04-13

Other References:

CHEE ET AL.: "Accessing genetic Information with High-density DNA arrays", SCIENCE, vol. 274, 25 October 1996 (1996-10-25), XP002022508, DOI: doi:10.1126/science.274.5287.610
"GeneChip Human Genome arrays. U133 A array", AFFYMETRIX DATA SHEET, 20 April 2001 (2001-04-20), pages 1 - 4
BLALOCK ET AL.: "Incipient Alzheimer's disease: Microarray correlation analyses reveal major transcriptional and tumor suppressor responses", PNAS, vol. 101, no. 7, 9 February 2004 (2004-02-09), pages 2173 - 2178, XP055073328, DOI: doi:10.1073/pnas.0308512100

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