Title:
BACTERIOPHAGE RESISTANCE INHIBITOR FOR FOOD POISONING BACTERIA AND USE OF INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2019/224941
Kind Code:
A1
Abstract:
Provided are: a novel, effective bacteriophage resistance inhibitor for food poisoning bacteria that is effective against a wide variety of food poisoning bacteria, and the use of said inhibitor; a composition for inhibiting proliferation of food poisoning bacteria; and a method for inhibiting bacteriophage resistance of food poisoning bacteria. The bacteriophage resistance inhibitor for food poisoning bacteria contains a chelating agent or nisin as an active ingredient. The composition for inhibiting proliferation of food poisoning bacterial includes a bacteriophage and the aformentioned bacteriophage resistance inhibitor for food poisoning bacteria. The use of the bacteriophage resistance inhibitor for food poisoning bacteria is specifically the use of a bacteriophage resistance inhibitor for food poisoning bacteria that contains a chelating agent or nisin as an active ingredient, and involves a use for inhibiting the food poisoning bacteria from developing resistance to the bacteriophage. The method for inhibiting bacteriophage resistance of food poisoning bacteria involves the use of a chelating agent or nisin.
Inventors:
MIYAMOTO TAKAHISA (JP)
Application Number:
PCT/JP2018/019836
Publication Date:
November 28, 2019
Filing Date:
May 23, 2018
Export Citation:
Assignee:
UNIV KYUSHU NAT UNIV CORP (JP)
International Classes:
C12N7/00; A23L3/3526; A23L3/3571; A61K31/198; A61K38/16; A61P31/04
Foreign References:
| JP2012517225A | 2012-08-02 | |||
| JP2014217336A | 2014-11-20 |
Other References:
DYKES, G. A. ET AL.: "Combined antimicrobial effect of nisin and a listeriophage against Listeria monocytogenes in broth but not in buffer or on raw beef", INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, vol. 73, no. 1, 2002, pages 71 - 81, XP055218865, DOI: 10.1016/S0168-1605(01)00710-3
LEVERENTZ, B. ET AL.: "Biocontrol of Listeria monocytogenes on Fresh-Cut Produce by Treatment with Lytic Bacteriophages and a Bacteriocin", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 69, no. 8, 2003, pages 4519 - 4526, XP001203576, DOI: 10.1128/AEM.69.8.4519-4526.2003
MARTINEZ, B. ET AL.: "Nisin-bacteriophage crossresistance in Staphylococcus aureus", INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, vol. 122, no. 3, 2008, pages 253 - 258, XP022500107, DOI: 10.1016/j.ijfoodmicro.2008.01.011
WANG, C. ET AL.: "Effects of Salmonella bacteriophage, nisin and potassium sorbate and their combination on safety and shelf life of fresh chilled pork", FOOD CONTROL, vol. 73, 2017, pages 869 - 877
DRILLING, A. ET AL.: "Safety and efficacy of topical bacteriophage and ethylenediaminetetraacetic acid treatment of Staphylococcus aureus infection in sheep model of sinusitis", INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, vol. 4, no. 3, 2014, pages 176 - 186
LEVERENTZ, B. ET AL.: "Biocontrol of Listeria monocytogenes on Fresh-Cut Produce by Treatment with Lytic Bacteriophages and a Bacteriocin", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 69, no. 8, 2003, pages 4519 - 4526, XP001203576, DOI: 10.1128/AEM.69.8.4519-4526.2003
MARTINEZ, B. ET AL.: "Nisin-bacteriophage crossresistance in Staphylococcus aureus", INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, vol. 122, no. 3, 2008, pages 253 - 258, XP022500107, DOI: 10.1016/j.ijfoodmicro.2008.01.011
WANG, C. ET AL.: "Effects of Salmonella bacteriophage, nisin and potassium sorbate and their combination on safety and shelf life of fresh chilled pork", FOOD CONTROL, vol. 73, 2017, pages 869 - 877
DRILLING, A. ET AL.: "Safety and efficacy of topical bacteriophage and ethylenediaminetetraacetic acid treatment of Staphylococcus aureus infection in sheep model of sinusitis", INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, vol. 4, no. 3, 2014, pages 176 - 186
Attorney, Agent or Firm:
TANAI Sumio et al. (JP)
Download PDF: