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Title:
BENZAMIDINE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/1999/064392
Kind Code:
A1
Abstract:
A benzamidine derivative represented by formula (I), analogs thereof and pharmaceutically acceptable salts thereof. Because of having an effect of inhibiting activated blood coagulation factor X, these compounds are useful as preventives and remedies for various diseases based on thrombus and embolus.

Inventors:
NAKAGAWA TADAKIYO (JP)
SAGI KAZUYUKI (JP)
YOSHIDA KAORU (JP)
FUKUDA YUMIKO (JP)
SHOJI MASATAKA (JP)
TAKEHANA SHUNJI (JP)
KAYAHARA TAKASHI (JP)
TAKAHARA AKIRA (JP)
Application Number:
PCT/JP1999/003055
Publication Date:
December 16, 1999
Filing Date:
June 08, 1999
Export Citation:
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Assignee:
AJINOMOTO KK (JP)
NAKAGAWA TADAKIYO (JP)
SAGI KAZUYUKI (JP)
YOSHIDA KAORU (JP)
FUKUDA YUMIKO (JP)
SHOJI MASATAKA (JP)
TAKEHANA SHUNJI (JP)
KAYAHARA TAKASHI (JP)
TAKAHARA AKIRA (JP)
International Classes:
C07C257/18; C07D207/48; C07D211/46; C07D233/26; C07D401/04; C07D401/06; C07D417/04; C07F9/40; C07F9/59; C07F9/6558; (IPC1-7): C07C257/18; A61K31/165; A61K31/40; A61K31/415; A61K31/44; A61K31/445; A61K31/50; A61K31/505; C07D207/48; C07D211/46; C07D233/26; C07D401/04; C07D401/06; C07D401/14; C07D417/04; C07F9/40
Domestic Patent References:
WO1996040744A11996-12-19
WO1996005189A11996-02-22
WO1998031661A11998-07-23
Other References:
See also references of EP 1086946A4
Attorney, Agent or Firm:
Nakamura, Minoru (Marunouchi 3-chome Chiyoda-ku Tokyo, JP)
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