Title:
BENZIMIDAZOLE OR AZABENZIMIDAZOLE-6-CARBOXYLIC ACID COMPOUND AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/000834
Kind Code:
A1
Abstract:
Provided in the present invention are a benzimidazole or azabenzimidazole-6-carboxylic acid compound and the use thereof, which benzimidazole or azabenzimidazole-6-carboxylic acid compound has a structure as shown in formula (I). The benzimidazole or azabenzimidazole-6-carboxylic acid compound can effectively activate a GLP-1R downstream signal pathway and improve the expression of cAMP, so that the effects of promoting insulin secretion and treating diabetes and complications thereof are achieved, and the benzimidazole or azabenzimidazole-6-carboxylic acid compound has a great application value.
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Inventors:
CAI XIONG (CN)
WENG YUNWO (CN)
LIN MINGSHENG (CN)
LIU BIN (CN)
HE QIJIE (CN)
QING YUANHUI (CN)
LIU YITING (CN)
FENG QIAO (CN)
TAN HUICHEN (CN)
DENG XINLAN (CN)
WU SHAOBIN (CN)
FAN FUSHUN (CN)
QIAN CHANGGENG (CN)
WENG YUNWO (CN)
LIN MINGSHENG (CN)
LIU BIN (CN)
HE QIJIE (CN)
QING YUANHUI (CN)
LIU YITING (CN)
FENG QIAO (CN)
TAN HUICHEN (CN)
DENG XINLAN (CN)
WU SHAOBIN (CN)
FAN FUSHUN (CN)
QIAN CHANGGENG (CN)
Application Number:
PCT/CN2022/096230
Publication Date:
January 26, 2023
Filing Date:
May 31, 2022
Export Citation:
Assignee:
BEBETTER MED INC (CN)
International Classes:
C07D471/04; A61K31/4439; A61K31/444; A61K31/454; A61K31/4545; A61K31/496; A61P3/10; C07D403/14; C07D405/14; C07D409/14; C07D471/14
Domestic Patent References:
| WO2020103815A1 | 2020-05-28 | |||
| WO2021018023A1 | 2021-02-04 | |||
| WO2020207474A1 | 2020-10-15 |
Foreign References:
| CN113480534A | 2021-10-08 | |||
| CN110325530A | 2019-10-11 |
Attorney, Agent or Firm:
GUANGZHOU PRIME IP LAW OFFICE (CN)
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