Title:
BENZIMIDAZOLE DERIVATIVE AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/111624
Kind Code:
A1
Abstract:
Disclosed are a compound of formula (I), a preparation method therefor, and a medical application thereof. In particular, provided are the compound of formula (I) or a stereoisomer, tautomer, or pharmaceutically acceptable salt thereof. These compounds are agonists of a glucagon-like peptide-1 receptor (GLP-1R). The present invention also relates to a pharmaceutical composition containing these compounds and use of the compound in a drug for treating diseases such as diabetes.
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Inventors:
WU JUNJUN (CN)
LU YINSUO (CN)
WU JIANLI (CN)
XIAO YING (CN)
XING WEI (CN)
LU YINSUO (CN)
WU JIANLI (CN)
XIAO YING (CN)
XING WEI (CN)
Application Number:
PCT/CN2021/133447
Publication Date:
June 02, 2022
Filing Date:
November 26, 2021
Export Citation:
Assignee:
SHENZHEN SALUBRIS PHARM CO LTD (CN)
International Classes:
C07D401/04; A61K31/497; A61P3/10; C07D405/04
Domestic Patent References:
| WO2020103815A1 | 2020-05-28 | |||
| WO2020207474A1 | 2020-10-15 | |||
| WO2019239371A1 | 2019-12-19 | |||
| WO2021018023A1 | 2021-02-04 | |||
| WO2021112538A1 | 2021-06-10 | |||
| WO2021081207A1 | 2021-04-29 | |||
| WO2021160127A1 | 2021-08-19 | |||
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| WO2009111700A2 | 2009-09-11 | |||
| WO2010114824A1 | 2010-10-07 | |||
| WO2011114271A1 | 2011-09-22 | |||
| WO2013090454A2 | 2013-06-20 | |||
| WO2018056453A1 | 2018-03-29 | |||
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| WO2019239319A1 | 2019-12-19 | |||
| WO2019239371A1 | 2019-12-19 | |||
| WO2020103815A1 | 2020-05-28 |
Foreign References:
| CN110325530A | 2019-10-11 | |||
| CN113493447A | 2021-10-12 | |||
| CN113480534A | 2021-10-08 | |||
| KR20210117194A | 2021-09-28 |
Other References:
LIPPINCOTTWILLIAMSWILKINS: "Remington: The Science and Practice of Pharmacy", 2005
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