Title:
BI-AROMATIC COMPOUNDS BOUND BY A HETEROETHYNYLENE RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME
Document Type and Number:
WIPO Patent Application WO1999010322
Kind Code:
B1
Abstract:
The invention concerns compounds of formula (I) in which: Ar represents a radical selected among formulae (a) to (c). Z being O, S, or N-R6; R1 represents in particular a halogen atom, -CH3, or carboxyl; R2 and R3 represent in particular H, alkyl, cycloalkyl; or R2 and R3 together form a cycle with 5 or 6 chains; R4 and R5 represent in particular H or a halogen atom; R6 represents in particular H or alkyl; X represents a radical Y-CC-; Y represents O, S(O)n or Se(O)n', n being 0, 1 or 2, and the salts of the compounds of formula (I). Said compounds can be used in particular for treating dermatological diseases related to keratinization disorder, and to fight against skin ageing.
Inventors:
BERNARDON JEAN-MICHEL (FR)
DIAZ PHILIPPE (FR)
DIAZ PHILIPPE (FR)
Application Number:
PCT/FR1998/001835
Publication Date:
April 08, 1999
Filing Date:
August 21, 1998
Export Citation:
Assignee:
GALDERMA RES & DEV (FR)
BERNARDON JEAN MICHEL (FR)
DIAZ PHILIPPE (FR)
BERNARDON JEAN MICHEL (FR)
DIAZ PHILIPPE (FR)
International Classes:
A61K8/00; A61K8/30; A61K8/36; A61K8/368; A61K8/37; A61K8/46; A61K8/49; A61K8/58; A61K31/05; A61K31/095; A61K31/10; C07D213/79; A61K31/11; A61K31/166; A61K31/19; A61K31/192; A61K31/235; A61K31/381; A61K31/44; A61K31/4433; A61P9/10; A61P17/00; A61P17/06; A61P17/10; A61P19/02; A61P35/00; A61Q19/00; C07C63/06; C07C69/76; C07C317/44; C07C323/56; C07C323/62; C07C391/00; C07C391/02; C07D213/24; C07D213/80; C07D213/82; C07D335/06; C07D409/12; A61Q19/08; (IPC1-7): C07C323/62; C07C317/44; C07C391/02; C07D213/80; C07D213/79; C07D213/82; C07D335/06; A61K31/19; A61K31/235; A61K31/44; A61K31/095
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