Title:
BIFIDOBACTERIUM LONGUM SUBSP. LONGUM I772, ISOLATION AND PURIFICATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/110282
Kind Code:
A1
Abstract:
A bifidobacterium longum subsp. longum i772, an isolation and purification method therefor and use thereof. The strain has been deposited in the China General Microbiological Culture Collection Center, with the deposit number of CGMCC NO. 19856. The bifidobacterium longum subsp. longum is obtained by enriching, screening and continuously purifying a target strain in the feces of breast-feeding infants or young children. Compared with the existing bifidobacterium longum subsp. longum, the screened bifidobacterium longum subsp. longum has the functions of regulating the intestinal flora balance and relieving the liver injury caused by alcohol. The strain is used for preparing beverages, foods, medicines or probiotic products having an intestinal regulation function.
Inventors:
FENG LILI (CN)
YUAN QINGBIN (CN)
WANG SHIJIE (CN)
WEI LIHUA (CN)
ZHANG DONG (CN)
XUE YULING (CN)
XUN YIPING (CN)
FENG XIAOYING (CN)
LIU YAOYAO (CN)
YUAN QINGBIN (CN)
WANG SHIJIE (CN)
WEI LIHUA (CN)
ZHANG DONG (CN)
XUE YULING (CN)
XUN YIPING (CN)
FENG XIAOYING (CN)
LIU YAOYAO (CN)
Application Number:
PCT/CN2020/134226
Publication Date:
June 02, 2022
Filing Date:
December 07, 2020
Export Citation:
Assignee:
JUNLEBAO DAIRY GROUP CO LTD (CN)
International Classes:
C12N1/20; A23L2/52; A23L33/135; A61K35/745; A61P1/00; C12N1/02; C12R1/01
Domestic Patent References:
| WO2014022279A1 | 2014-02-06 | |||
| WO2019112054A1 | 2019-06-13 |
Foreign References:
| CN111479579A | 2020-07-31 | |||
| CN108486000A | 2018-09-04 | |||
| CN1500146A | 2004-05-26 | |||
| CN103599135A | 2014-02-26 | |||
| CN109929773A | 2019-06-25 | |||
| CN111543640A | 2020-08-18 |
Other References:
WANG KAICEN, LV LONGXIAN, YAN REN, WANG QIANGQIANG, JIANG HUIYONG, WU WENRUI, LI YATING, YE JIANZHONG, WU JINGJING, YANG LIYA, BIA: "Bifidobacterium longum R0175 Protects Rats against d-Galactosamine-Induced Acute Liver Failure", MSPHERE, AMERICAN SOCIETY FOR MICROBIOLOGY, WASHINGTON, vol. 5, no. 1, 26 February 2020 (2020-02-26), Washington , pages 1 - 14, XP055934701, ISSN: 2379-5042, DOI: 10.1128/mSphere.00791-19
YI HONG-WEI; ZHU XIAO-XIAO; HUANG XIAO-LI; LAI YU-ZHU; TANG YUE: "Selenium-enriched Bifidobacterium longum protected alcohol and high fat diet induced hepatic injury in mice", CHINESE JOURNAL OF NATURAL MEDICINES, ELSEVIER, AMSTERDAM, NL, vol. 18, no. 3, 1 March 2020 (2020-03-01), AMSTERDAM, NL, pages 169 - 177, XP086123189, ISSN: 1875-5364, DOI: 10.1016/S1875-5364(20)30018-2
TIAN XIAOZHU; LI RONG; JIANG YIMING; ZHAO FEI; YU ZHENGSHENG; WANG YIQING; DONG ZIXING; LIU PU; LI XIANGKAI: "Bifidobacterium breve ATCC15700 pretreatment prevents alcoholic liver disease through modulating gut microbiota in mice exposed to chronic alcohol intake", JOURNAL OF FUNCTIONAL FOODS, ELSEVIER BV, NL, vol. 72, 22 June 2020 (2020-06-22), NL , XP086219844, ISSN: 1756-4646, DOI: 10.1016/j.jff.2020.104045
KWON EUN KYUNG; KANG GEUM-DAN; KIM WON-KYEONG; HAN MYUNG JOO; KIM DONG-HYUN: "Lactobacillus plantarumLC27 andBifidobacterium longumLC67 simultaneously alleviate ethanol-induced gastritis and hepatic injury in mice", JOURNAL OF FUNCTIONAL FOODS, ELSEVIER BV, NL, vol. 38, 1 January 1900 (1900-01-01), NL , pages 389 - 398, XP085246677, ISSN: 1756-4646, DOI: 10.1016/j.jff.2017.09.036
YI HONG-WEI; ZHU XIAO-XIAO; HUANG XIAO-LI; LAI YU-ZHU; TANG YUE: "Selenium-enriched Bifidobacterium longum protected alcohol and high fat diet induced hepatic injury in mice", CHINESE JOURNAL OF NATURAL MEDICINES, ELSEVIER, AMSTERDAM, NL, vol. 18, no. 3, 1 March 2020 (2020-03-01), AMSTERDAM, NL, pages 169 - 177, XP086123189, ISSN: 1875-5364, DOI: 10.1016/S1875-5364(20)30018-2
TIAN XIAOZHU; LI RONG; JIANG YIMING; ZHAO FEI; YU ZHENGSHENG; WANG YIQING; DONG ZIXING; LIU PU; LI XIANGKAI: "Bifidobacterium breve ATCC15700 pretreatment prevents alcoholic liver disease through modulating gut microbiota in mice exposed to chronic alcohol intake", JOURNAL OF FUNCTIONAL FOODS, ELSEVIER BV, NL, vol. 72, 22 June 2020 (2020-06-22), NL , XP086219844, ISSN: 1756-4646, DOI: 10.1016/j.jff.2020.104045
KWON EUN KYUNG; KANG GEUM-DAN; KIM WON-KYEONG; HAN MYUNG JOO; KIM DONG-HYUN: "Lactobacillus plantarumLC27 andBifidobacterium longumLC67 simultaneously alleviate ethanol-induced gastritis and hepatic injury in mice", JOURNAL OF FUNCTIONAL FOODS, ELSEVIER BV, NL, vol. 38, 1 January 1900 (1900-01-01), NL , pages 389 - 398, XP085246677, ISSN: 1756-4646, DOI: 10.1016/j.jff.2017.09.036
Attorney, Agent or Firm:
SHIJIAZHUANG KECHENG PATENT OFFICE (GENERAL PARTNERSHIP) (CN)
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