Title:
BIOMARKER MICRORNA FOR DIAGNOSING TUBERCULOSIS
Document Type and Number:
WIPO Patent Application WO/2017/026606
Kind Code:
A1
Abstract:
The present invention relates to a microRNA composition, which can be used as a biomarker useful for early diagnosis of tuberculosis, and to a tuberculosis diagnostic kit which can measure an expression level thereof. More specifically, the present invention relates to a biomarker composition for diagnosing tuberculosis, which comprises miRNA-302f of SEQ ID NO: 1, wherein an expression decreases due to tuberculosis infection, and to a tuberculosis diagnostic kit which can measure an expression level thereof.
Inventors:
LEE HYE-MI (KR)
JO EUN-KYEONG (KR)
KIM JIN-MAN (KR)
SOHN KYUNG MOK (KR)
JO EUN-KYEONG (KR)
KIM JIN-MAN (KR)
SOHN KYUNG MOK (KR)
Application Number:
PCT/KR2016/000488
Publication Date:
February 16, 2017
Filing Date:
January 18, 2016
Export Citation:
Assignee:
THE IND & ACAD COOP IN CHUNGNAM NAT UNIV (IAC) (KR)
International Classes:
C12Q1/68
Domestic Patent References:
| WO2012012694A2 | 2012-01-26 |
Foreign References:
| KR101476781B1 | 2014-12-29 | |||
| US20140121133A1 | 2014-05-01 |
Other References:
MIOTIO ET AL.: "miRNA Signatures in Sera of Patients with Active Pulmonary Tuberculosis", PLOS ONE, vol. 8, no. 11, 21 November 2013 (2013-11-21), pages 1 - 15, XP055363469
UEBERBERG ET AL.: "Are microRNAs Suitable Biomarkers of Immunity to Tuberculosis?", MOLECULAR AND CELLULAR PEDIATRICS, vol. 1, 2014, pages 1 - 6, XP055363470
XU ET AL.: "Tuberculosis-related miRNAs Have Potential as Disease Biomarksers", JOURNAL OF TUBERCULOSIS RESEARCH, vol. 1, no. 2, 2013, pages 17 - 27, XP055363471
UEBERBERG ET AL.: "Are microRNAs Suitable Biomarkers of Immunity to Tuberculosis?", MOLECULAR AND CELLULAR PEDIATRICS, vol. 1, 2014, pages 1 - 6, XP055363470
XU ET AL.: "Tuberculosis-related miRNAs Have Potential as Disease Biomarksers", JOURNAL OF TUBERCULOSIS RESEARCH, vol. 1, no. 2, 2013, pages 17 - 27, XP055363471
Attorney, Agent or Firm:
KIM, Wonjoon (KR)
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