CELLS EXPRESSING ANTI-Fc RECEPTOR BINDING COMPONENTS

Title:

CELLS EXPRESSING ANTI-Fc RECEPTOR BINDING COMPONENTS

Document Type and Number:

WIPO Patent Application WO1999028349

Kind Code:

A3

Abstract:

Cells transformed to express on their surface a component which binds to an Fc receptor of an effector cell are disclosed. Also disclosed are expression vectors used to transform the cells. Once transformed, the cells bind to effector cells via the Fc receptor of the effector cell to stimulate an effector cell mediated immune response.

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Inventors:

KELER TIBOR (US)
GOLDSTEIN JOEL (US)
GRAZIANO ROBERT (US)
DEO YASHWANT M (US)

Application Number:

PCT/US1998/025556

Publication Date:

November 18, 1999

Filing Date:

December 02, 1998

Export Citation:

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Assignee:

MEDAREX INC (US)
KELER TIBOR (US)
GOLDSTEIN JOEL (US)
GRAZIANO ROBERT (US)
DEO YASHWANT M (US)

International Classes:

C12N15/09; A61K35/12; A61K39/00; A61K39/44; A61P37/04; A61P43/00; C07K14/71; C07K16/28; C12N5/10; A61K38/00; (IPC1-7): C12N5/22; C07K16/28; A61K39/00

Domestic Patent References:

WO1992005793A1

1992-04-16

Foreign References:

DE19634159C1	1997-09-25
US5635600A	1997-06-03

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