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Title:
CAPSULE FOR INHALATION WITH IMPROVED STABILITY OF COMBINED ACTIVE INGREDIENTS
Document Type and Number:
WIPO Patent Application WO/2016/159542
Kind Code:
A1
Abstract:
A capsule for inhalation is provided. The capsule includes dry powder for inhalation, the dry powder including: at least two combined active ingredients selected from the group consisting of salmeterol or a pharmaceutically acceptable salt thereof, tiotropium or a pharmaceutically acceptable salt thereof, and fluticasone or a pharmaceutically acceptable salt thereof; and a diluent, wherein the dry powder is filled in a hydroxypropyl methylcellulose (HPMC) hard capsule not containing a gelation agent or in a HPMC hard capsule containing gellan gum as a gelation agent.

Inventors:
YOON YOUNG MIN (KR)
CHO HYUK JUN (KR)
IM HO TAEK (KR)
KIM YONG IL (KR)
PARK JAE HYUN (KR)
WOO JONG SOO (KR)
Application Number:
PCT/KR2016/002623
Publication Date:
October 06, 2016
Filing Date:
March 16, 2016
Export Citation:
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Assignee:
HANMI PHARM IND CO LTD (KR)
International Classes:
A61K9/00; A61K9/50; A61K31/135; A61K31/46; A61K31/56; A61K47/10; A61K47/26; A61K47/48
Foreign References:
KR20130140358A2013-12-24
KR20050003416A2005-01-10
KR20040097348A2004-11-17
KR20130029760A2013-03-25
Other References:
AL-TABAKHA, M. M. ET AL.: "HPMC capsules: current status and future prospects.", JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES, vol. 13, no. 3, 2010, pages 428 - 442, XP055198323
Attorney, Agent or Firm:
Y.P.LEE, MOCK & PARTNERS (13 Eonju-ro 30-gilGangnam-gu, Seoul, KR)
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