Title:
CARBAZOLE AND CYCLOPENTAINDOLE DERIVATIVES TO TREAT INFECTION WITH HEPATITIS C VIRUS
Document Type and Number:
WIPO Patent Application WO2006034337
Kind Code:
A3
Abstract:
The invention is directed to a method of treating, preventing, or inhibiting a Hepatitis C viral infection in a mammal comprising contacting the mammal with an effective amount of a compound of the formula (I) wherein substitutions at R1 - R13, m and Y are set forth in the specification
Inventors:
GOPALSAMY ARIAMALA (US)
CISZEWSKI GREGORY MARK (US)
SHI MENGXIAO (US)
PARK KAAPJOO (US)
CISZEWSKI GREGORY MARK (US)
SHI MENGXIAO (US)
PARK KAAPJOO (US)
Application Number:
PCT/US2005/033803
Publication Date:
September 14, 2006
Filing Date:
September 21, 2005
Export Citation:
Assignee:
WYETH CORP (US)
GOPALSAMY ARIAMALA (US)
CISZEWSKI GREGORY MARK (US)
SHI MENGXIAO (US)
PARK KAAPJOO (US)
GOPALSAMY ARIAMALA (US)
CISZEWSKI GREGORY MARK (US)
SHI MENGXIAO (US)
PARK KAAPJOO (US)
International Classes:
A61K31/404; A61K31/403; A61P31/14; C07D209/88
Domestic Patent References:
| WO2005072408A2 | 2005-08-11 | |||
| WO1998038986A2 | 1998-09-11 |
Foreign References:
| US5830911A | 1998-11-03 | |||
| EP0307077A1 | 1989-03-15 |
Other References:
GOPALSAMY ARIAMALA ET AL: "Identification of carbazole and cyclopentaindole derivatives as inhibitors of HCV RNA dependent RNA polymerase.", ABSTRACTS OF PAPERS AMERICAN CHEMICAL SOCIETY, vol. 229, no. Part 2, March 2005 (2005-03-01), & 229TH NATIONAL MEETING OF THE AMERICAN-CHEMICAL-SOCIETY; SAN DIEGO, CA, USA; MARCH 13 -17, 2005, pages U167, XP008065271, ISSN: 0065-7727
RAJ K ET AL: "NU- & OMICRON-DIALKYLAMINOALKYLCARBAXOLES AS POTENTIAL ANTIVIRAL AGENTS", INDIAN JOURNAL OF CHEMISTRY, SECTION B: ORGANIC, INCL. MEDICINAL, PUBLICATIONS & INFORMATIONS DIRECTORATE, NEW DELHI, IN, vol. 14B, no. 5, 1 May 1976 (1976-05-01), pages 371 - 373, XP000196847, ISSN: 0019-5103
RAJ K ET AL: "NU- & OMICRON-DIALKYLAMINOALKYLCARBAXOLES AS POTENTIAL ANTIVIRAL AGENTS", INDIAN JOURNAL OF CHEMISTRY, SECTION B: ORGANIC, INCL. MEDICINAL, PUBLICATIONS & INFORMATIONS DIRECTORATE, NEW DELHI, IN, vol. 14B, no. 5, 1 May 1976 (1976-05-01), pages 371 - 373, XP000196847, ISSN: 0019-5103
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