Title:
CARDIAC SAFE, RAPID MEDICATION DELIVERY
Document Type and Number:
WIPO Patent Application WO2006044421
Kind Code:
A3
Abstract:
The disclosure provides methods and compositions for providing an effective dose of an active agent and/or drug composition to a subject by inhalation. The methods of the disclosure are useful in determining a maximal effective dose that limits cardiovascular damage upon inhalation.
Inventors:
RABINOWITZ JOSHUA D (US)
LLOYD PETER M (US)
LLOYD PETER M (US)
Application Number:
PCT/US2005/036587
Publication Date:
August 03, 2006
Filing Date:
October 12, 2005
Export Citation:
Assignee:
ALEXZA PHARMACEUTICALS INC (US)
RABINOWITZ JOSHUA D (US)
LLOYD PETER M (US)
RABINOWITZ JOSHUA D (US)
LLOYD PETER M (US)
International Classes:
A61K9/00; A61M15/02; A61P1/08; A61P1/14; A61P5/00; A61P9/00; A61P11/00; A61P15/00; A61P23/00; A61P25/08; A61P27/02; A61P35/00; A61P39/02
Foreign References:
| US20030017120A1 | 2003-01-23 |
Other References:
THOMSON P.D.R.: "Physican's Desk Reference", vol. 57TH ED., 2003, MONTVALE, NJ, pages: 1542 - 1550, XP008085040
HOCHHAUS G. ET AL.: "Pharmacokinetic/Dynamic Correlation of Pulmonary and Cardiac Effects of Fenoterol in Asthmatic Patients After Different Routes of Administration", PHARMACEUTICAL RESEARCH, vol. 9, no. 3, 1992, pages 291 - 297, XP008085060
HOCHHAUS G. ET AL.: "Pharmacokinetic/Dynamic Correlation of Pulmonary and Cardiac Effects of Fenoterol in Asthmatic Patients After Different Routes of Administration", PHARMACEUTICAL RESEARCH, vol. 9, no. 3, 1992, pages 291 - 297, XP008085060
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