WO1987004617A1 | 1987-08-13 | |||
WO2004000291A1 | 2003-12-31 |
1. | The compositions of the admitted formulae. |
2. | The indications included. Urea, propylene glycol and lactic acid base was used with the following active ingredients: Corticosteroids, topical: Antibacterial, topical: Antifungal, topical. |
Technical Field
A new pharmaceutical product to minimize the side effects encountered with the use of local products via using a special carrier vehicle, composed of urea, propylene glycol and lactic acid.
Background Art
Minimizing the side effects encountered with the use of local products via using a special carrier vehicle, composed of urea, propylene glycol and lactic acid. This vehicle, gives many benefits, such as: 1. Enhancing the penetrability of these active ingredients. 2. Adding antibacterial, antifungal or anti-inflammatory effect to the formula. 3. The possibility of lowering the dose and/or duration of treatment. 4. Adding a cosmetic effect to the skin. Topical active ingredients used are in the following categories: 1. Anti-inflammatory. 2. Antifungal. 3. Antibacterial.
Disclosure of the Invention
Adding these active ingredients to the special vehicle was through three stages: I. Chemical- Pharmaceutical phase; determining the compatibility and possibility of using the vehicle for these active ingredients. II. Pharmacological- Toxicological phase; determining in vivo and in vitro studies to show primary effects. III. Clinical phase; undergoing double-blind, placebo- controlled, multi- centered study in three Egyptian Universities, to assure the clinical results. Urea, propylene glycol and lactic acid base was used with the following active ingredients: Corticosteroids, topical:
Antibacterial, topical:
Antifungal, topical
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