Title:
CELL-DERIVED VESICLES CONTAINING CATIONIC LIPID AND NUCLEIC ACID MOLECULE, AND PREPARATION METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/244084
Kind Code:
A1
Abstract:
The present invention relates to: cell-derived vesicles (CDVs) comprising a cationic lipid and an anionic nucleic acid molecule, wherein the cell-derived vesicles can be used as gene carriers; and a preparation method thereof. The gene carriers according to the present invention are characterized in that the anionic nucleic acid forms a complex with the cationic lipid, and the complex is loaded on the cell-derived vesicles.
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Inventors:
PARK JINHEE (KR)
LEE JI EUN (KR)
JANG EUN HYANG (KR)
OH SEUNG WOOK (KR)
PARK SUNG-SOO (KR)
BAE SHIN GYU (KR)
LEE JI EUN (KR)
JANG EUN HYANG (KR)
OH SEUNG WOOK (KR)
PARK SUNG-SOO (KR)
BAE SHIN GYU (KR)
Application Number:
PCT/KR2023/008398
Publication Date:
December 21, 2023
Filing Date:
June 16, 2023
Export Citation:
Assignee:
MDIMUNE INC (KR)
International Classes:
C12N15/87; C12N15/11; C12N15/113
Foreign References:
| KR20220061286A | 2022-05-12 | |||
| US20180036240A1 | 2018-02-08 | |||
| KR20220078565A | 2022-06-10 | |||
| KR20100085079A | 2010-07-28 |
Other References:
XU HUIYING, LIAO CHONG, LIANG SHIFU, YE BANG-CE: "A Novel Peptide-Equipped Exosomes Platform for Delivery of Antisense Oligonucleotides", APPLIED MATERIALS & INTERFACES, AMERICAN CHEMICAL SOCIETY, US, vol. 13, no. 9, 10 March 2021 (2021-03-10), US , pages 10760 - 10767, XP093117325, ISSN: 1944-8244, DOI: 10.1021/acsami.1c00016
Attorney, Agent or Firm:
LEE, Myoung-Jin (KR)
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