Title:
CELL FUSION PROMOTER AND UTILIZATION OF THE SAME
Document Type and Number:
WIPO Patent Application WO/2006/011354
Kind Code:
A1
Abstract:
It is intended to provide a regeneration promoter for regenerating a tissue with the use of somatic stem cells. It is also intended to provide a cell fusion promoter safely usable in vivo. Namely, it is intended to provide a cell fusion promoter comprising ATP or its metabolite. A cell fusion promoter comprising ATP or its metabolite and a method of producing fused cells in the presence of ATP or its metabolite. A medicinal composition for regenerating or improving the function of a tissue or an organ, which suffers from dysfunction or hypofunction due to injury or denaturation, by using stem cells. This composition comprises ATP or its metabolite and a pharmaceutically acceptable carrier.
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Inventors:
MINAMINO TETSUO (JP)
KITAKAZE MASASHI (JP)
HIRATA AKIO (JP)
KITAKAZE MASASHI (JP)
HIRATA AKIO (JP)
Application Number:
PCT/JP2005/012799
Publication Date:
February 02, 2006
Filing Date:
July 12, 2005
Export Citation:
Assignee:
KOWA CO (JP)
MINAMINO TETSUO (JP)
KITAKAZE MASASHI (JP)
HIRATA AKIO (JP)
MINAMINO TETSUO (JP)
KITAKAZE MASASHI (JP)
HIRATA AKIO (JP)
International Classes:
A61K31/7076; A61K35/28; A61K35/34; A61L27/00; A61L27/38; A61L27/54; A61P43/00; C12N5/07; C12N5/074; C12N5/077; C12N5/0775; C12N5/095; (IPC1-7): C12N15/02; A61K9/08; A61K9/19; A61K31/7076; A61K35/12; A61L27/00; A61P9/04; C12N5/10
Foreign References:
| JP2005506845A | 2005-03-10 |
Other References:
HORI M. ET AL: "Adenosine, the heart and coronary circulation.", HYPERTENSION., vol. 18, no. 5, 1991, pages 565 - 574, XP002999529
SANADA S. ET AL: "Adenosine to Shinkin Hogo-Precondition tono Kakawari.", JAPANESE SOCIETY OF CLINICAL PHYSIOLOGY ZASSHI., vol. 31, no. 2, 2001, pages 73 - 78, XP002999530
SANADA S. ET AL: "Adenosine to Shinkin Hogo-Precondition tono Kakawari.", JAPANESE SOCIETY OF CLINICAL PHYSIOLOGY ZASSHI., vol. 31, no. 2, 2001, pages 73 - 78, XP002999530
Attorney, Agent or Firm:
Saeki, Norio (Aminosan Kaikan Building 15-, Nihonbashi 3-chome Tokyo, JP)
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