Title:
CELL GROWTH INHIBITORY MEMBER, CELL METASTASIS INHIBITORY MEMBER, METHOD OF INHIBITING CELL GROWTH, METHOD OF INHIBITING CELL METASTASIS, LAYERED FILM AND MEDICAL INSTRUMENT
Document Type and Number:
WIPO Patent Application WO/2006/118248
Kind Code:
A1
Abstract:
(1) A cell growth inhibitory member characterized by having a porous structure; (2) a method of inhibiting cell growth characterized by comprising bringing a part having the porous structure formed therein of the above cell growth inhibitory member into contact with cells and thus inhibiting the growth of the cells in the contact part; (3) a layered film composed of a first resin film and a second resin film, which is the above cell growth inhibitory member, layered thereon; (4) a cell metastasis inhibitory member characterized by having a porous structure; (5) a method of inhibiting cell metastasis characterized by comprising bringing a part having the porous structure formed therein of the above cell metastasis inhibitory member into contact with cells and thus inhibiting the metastasis of the cells in the contact part; (6) a layered film composed of a first resin film and a second resin film, which is the above cell metastasis inhibitory member, layered thereon; and (7) a medical instrument characterized in that the surface of the medical instrument is entirely or partly coated with the above cell growth inhibitory member or the above cell metastasis inhibitory member. Thus, an excellent cell growth inhibitory effect or an excellent cell metastasis inhibitory effect can be obtained without resorting to a physiologically active substance such as carcinostatic agent.
Inventors:
TANAKA MASARU (JP)
HAMADA JUNICHI
TOYOKAWA YOSHIHIDE (JP)
YAMAMOTO SADA-AKI
SHIMOMURA MASATSUGU
HAMADA JUNICHI
TOYOKAWA YOSHIHIDE (JP)
YAMAMOTO SADA-AKI
SHIMOMURA MASATSUGU
Application Number:
PCT/JP2006/308980
Publication Date:
November 09, 2006
Filing Date:
April 28, 2006
Export Citation:
Assignee:
JAPAN SCIENCE & TECH AGENCY (JP)
UNIV HOKKAIDO NAT UNIV CORP (JP)
ZEON MEDICAL INC (JP)
TANAKA MASARU (JP)
HAMADA JUNICHI
TOYOKAWA YOSHIHIDE (JP)
YAMAMOTO SADA-AKI
SHIMOMURA MASATSUGU
UNIV HOKKAIDO NAT UNIV CORP (JP)
ZEON MEDICAL INC (JP)
TANAKA MASARU (JP)
HAMADA JUNICHI
TOYOKAWA YOSHIHIDE (JP)
YAMAMOTO SADA-AKI
SHIMOMURA MASATSUGU
International Classes:
A61L29/00; A61B17/00; A61F2/91; A61L31/00
Domestic Patent References:
| WO2004089434A1 | 2004-10-21 | |||
| WO2005051450A1 | 2005-06-09 | |||
| WO2003045973A2 | 2003-06-05 | |||
| WO1995009883A1 | 1995-04-13 |
Foreign References:
| JP2001157574A | 2001-06-12 | |||
| JP2002347107A | 2002-12-04 |
Other References:
SUNAMI H. ET AL.: "Saibo Zoshoku o Seigyo shiuru Saibogai Matrix (ECM) Kyuchaku Honeycomb Film no Sakusei", THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ZASSHI, vol. 4, no. SUPPL., 10 February 2005 (2005-02-10), pages 100, XP003004633
SATO K. ET AL.: "Seibunkaisei Kobunshi o Mochiita Takosei scaffold ni yoru Saibo Secchaku.Keitai no Seigyo", THE JAPANESE JOURNAL OF ARTIFICIAL ORGANS (JAPANES SOCIETY FOR ARTIFICIAL ORGANS), vol. 31, no. 2, 2002, pages S-86, XP003004634
SATO K. ET AL.: "Seibunkaisei Kobunshi o Mochiita Takosei scaffold no Kokei Seigyo ni yoru Saibo Secchaku.Keitai no Henka. (Preparation of the honeycomb patterned porous films of biodegradable polymer for tissue engineering scaffolds)", CSJ: THE CHEMICAL SOCIETY OF JAPAN KOENSHU, vol. 83, no. 2, 2002, pages 958, XP003004635
SATO K. ET AL.: "Seibunkaisei Kobunshi o Mochiita Takosei scaffold no Sakusei to Saibo Secchaku.Keitai no Henka. (Cell adhesion and morphology on porous scaffolds of biodegadable polymers)", CSJ: THE CHEMICAL SOCIETY OF JAPAN KOENSHU, vol. 82, 2003, pages 138, XP003004636
SUNAMI H. ET AL.: "Saibogai Matrix Kyuchaku Honeycomb Film o Mochiita Saibo Zoshoku no Seigyo. (Control of the cell proliferation by using ECM adsorbed honeycomb films)", POLYMER PREPRINTS, JAPAN, vol. 54, no. 1, 10 May 2005 (2005-05-10), pages 2232, XP003004637
SATO K. ET AL.: "Seibunkaisei Kobunshi o Mochiita Takosei scaffold ni yoru Saibo Secchaku.Keitai no Seigyo", THE JAPANESE JOURNAL OF ARTIFICIAL ORGANS (JAPANES SOCIETY FOR ARTIFICIAL ORGANS), vol. 31, no. 2, 2002, pages S-86, XP003004634
SATO K. ET AL.: "Seibunkaisei Kobunshi o Mochiita Takosei scaffold no Kokei Seigyo ni yoru Saibo Secchaku.Keitai no Henka. (Preparation of the honeycomb patterned porous films of biodegradable polymer for tissue engineering scaffolds)", CSJ: THE CHEMICAL SOCIETY OF JAPAN KOENSHU, vol. 83, no. 2, 2002, pages 958, XP003004635
SATO K. ET AL.: "Seibunkaisei Kobunshi o Mochiita Takosei scaffold no Sakusei to Saibo Secchaku.Keitai no Henka. (Cell adhesion and morphology on porous scaffolds of biodegadable polymers)", CSJ: THE CHEMICAL SOCIETY OF JAPAN KOENSHU, vol. 82, 2003, pages 138, XP003004636
SUNAMI H. ET AL.: "Saibogai Matrix Kyuchaku Honeycomb Film o Mochiita Saibo Zoshoku no Seigyo. (Control of the cell proliferation by using ECM adsorbed honeycomb films)", POLYMER PREPRINTS, JAPAN, vol. 54, no. 1, 10 May 2005 (2005-05-10), pages 2232, XP003004637
Attorney, Agent or Firm:
Ohishi, Haruhito (6-1 Uchikanda 3-chom, Chiyoda-ku Tokyo 47, JP)
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