Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
CELLULAR MATRIX NERVE GRAFT FOR REPAIRING PERIPHERAL NERVE INJURY AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2024/037293
Kind Code:
A1
Abstract:
Disclosed are a cellular matrix nerve graft for repairing peripheral nerve injury and a preparation method therefor. The cellular matrix nerve graft comprises an acellular matrix and a scaffold, wherein the acellular matrix is obtained by decellularization of the matrix secreted by stem cells, and the acellular matrix is wrapped around the scaffold. With the graft, the defects of autologous nerve transplantation repair can be overcome, and the immunogenicity of allogeneic cell transplantation repair is avoided. The present invention provides a cellular matrix nerve graft conducive to nerve cell proliferation and migration, which can establish a microenvironment conducive to axon growth, thereby achieving the purposes of nerve regeneration and function repair. The present invention provides a feasible solution for clinical treatment of nerve defects.

Inventors:
LI MEIYUAN (CN)
GU XIAOSONG (CN)
XU LINGCHI (CN)
GONG LEILEI (CN)
SUN HUALIN (CN)
WANG SHANSHAN (CN)
WANG HONGKUI (CN)
QIAN TIANMEI (CN)
XU LAI (CN)
Application Number:
PCT/CN2023/109010
Publication Date:
February 22, 2024
Filing Date:
July 25, 2023
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
UNIV NANTONG (CN)
International Classes:
A61L27/20; A61L27/36; A61L27/24; A61L27/50; A61L27/58
Foreign References:
CN115337458A2022-11-15
CN103041450A2013-04-17
CN112546303A2021-03-26
CN110584829A2019-12-20
US20030171824A12003-09-11
CN102218160A2011-10-19
JP2009045221A2009-03-05
US20080213389A12008-09-04
Attorney, Agent or Firm:
NANJING ZONGHENG INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
Download PDF:
View/Download PDF      PDF Help



 
Previous Patent: USER PLANE DATA STORAGE AND FORWARDING METHOD AND SYSTEM

Next Patent: BRUSHLESS MOTOR OF HIGH-SPEED HAIR DRYER