Title:
CENTRAL NERVOUS SYSTEM POTENTIATING COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2021/193703
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a safe, effective central nervous system potentiating composition. Provided according to the present invention is a central nervous system potentiating composition that contains, as an active ingredient, 2-(3,4-dihydroxyphenyl)chromenylium-3,5,7-triol, 2-(3,4,5-trihydroxylphenyl)chromenylium-3,5,7-triol, or a compound in which 2-15 molecules of (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromen-3,5,7-triol are condensed by a 4β→8 bond, or salts, hydrates, solvates, or polymorphs of these, the composition modulating autonomic nervous activity via production of superoxide and/or hydrogen peroxide.
Inventors:
OSAKABE NAOMI (JP)
FUJII YASUYUKI (JP)
FUSHIMI TAIKI (JP)
FUJII YASUYUKI (JP)
FUSHIMI TAIKI (JP)
Application Number:
PCT/JP2021/012174
Publication Date:
September 30, 2021
Filing Date:
March 24, 2021
Export Citation:
Assignee:
SHIBAURA INST TECH (JP)
International Classes:
A61K31/353; A23L33/10; A61K8/49; A61P3/06; A61P9/12; A61P21/00; A61P25/00; A61P25/28; A61P43/00
Foreign References:
| JP2019500001A | 2019-01-10 | |||
| JP2019505484A | 2019-02-28 |
Other References:
TSUJIMOTO YUJI: "Formation of Reactive Oxygen Species in Beverages and Beverage Model Systems and Suppression Thereof – Benzene Formation in Soft Drinks –", SEIKATSU EISEI, 1 January 2009 (2009-01-01), XP055861396, Retrieved from the Internet [retrieved on 20211115]
KIYONAKA SHIGEKI: "TRP channel activated by active oxygen", FARUMASHIA, 1 January 2012 (2012-01-01), pages 31 - 36, XP055861400, Retrieved from the Internet [retrieved on 20211115]
KIYONAKA SHIGEKI: "TRP channel activated by active oxygen", FARUMASHIA, 1 January 2012 (2012-01-01), pages 31 - 36, XP055861400, Retrieved from the Internet
Attorney, Agent or Firm:
SIKS & CO. (JP)
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