Title:
CHEMICALLY-MODIFIED ANTIMICROBIAL PEPTIDES, COMPOSITIONS AND METHODS OF PRODUCTION AND USE
Document Type and Number:
WIPO Patent Application WO2001098362
Kind Code:
A3
Abstract:
Compositions and methods for inhibiting and controlling the growth of microbes are disclosed. The composition comprises at least one chemically-modified peptide with antimicrobial activity and at least one carrier. The method comprises of administering an amount, effective for the prevention, inhibition and termination of microbial growth for industrial, pharmaceutical, household and personal care use.
Inventors:
KUHNER CARLA H
ROMESSER JAMES A
ROMESSER JAMES A
Application Number:
PCT/US2001/019400
Publication Date:
December 05, 2002
Filing Date:
June 15, 2001
Export Citation:
Assignee:
HERCULES INC (US)
International Classes:
A01N31/08; A01N33/12; A01N33/18; A01N33/20; A01N35/02; A01N37/46; A01N43/64; A01N43/76; A61K47/48; A01N43/80; A01N47/44; A01N47/46; A01N55/04; A01N59/08; A01N59/26; A61K8/00; A61K8/02; A61K8/06; A61K8/26; A61K8/30; A61K8/40; A61K8/44; A61K8/64; A61K8/72; A61K31/198; A61K31/405; A61K31/4172; A61K38/00; A61L15/07; A61L15/58; A61L29/00; A61L31/00; A61P1/02; A61P1/04; A61P9/00; A61P9/02; A61P11/00; A61P11/02; A61P13/02; A61P15/00; A61P15/06; A61P15/14; A61P17/02; A61P17/10; A61P19/00; A61P19/02; A61P27/02; A61P27/16; A61P31/00; A61P31/04; A61P31/06; A61P31/08; A61P31/10; A61P31/12; A61P31/14; A61P31/16; A61P31/18; A61P31/20; A61P31/22; A61P33/00; A61P33/02; A61P33/04; A61P33/10; A61P33/12; A61Q1/00; A61Q1/02; A61Q1/04; A61Q1/08; A61Q1/10; A61Q5/02; A61Q11/00; A61Q15/00; A61Q17/04; A61Q19/00; A61Q19/10; C02F1/50; C07K5/06; C07K5/062; C07K5/065; C07K5/068; C07K5/072; C07K5/078; C07K5/09; C07K5/11; C07K7/06; C07K17/08; (IPC1-7): C07K5/068; C07K5/09; C07K5/11; A61K38/04; A61P31/00; A61K47/48; C07C233/47; C07C279/14
Domestic Patent References:
| WO1999037667A1 | 1999-07-29 | |||
| WO2000059527A1 | 2000-10-12 | |||
| WO1996040768A2 | 1996-12-19 | |||
| WO1995019370A1 | 1995-07-20 | |||
| WO1992001462A1 | 1992-02-06 | |||
| WO1998007745A2 | 1998-02-26 | |||
| WO1999014231A2 | 1999-03-25 | |||
| WO2000000214A2 | 2000-01-06 |
Foreign References:
| US3265682A | 1966-08-09 | |||
| EP0618225A1 | 1994-10-05 | |||
| GB1237918A | 1971-07-07 | |||
| US5440016A | 1995-08-08 | |||
| US4448715A | 1984-05-15 | |||
| EP0280610A1 | 1988-08-31 | |||
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Other References:
DATABASE WPI Section Ch Week 199936, Derwent World Patents Index; Class B05, AN 1999-430213, XP002203218
DATABASE MEDLINE [online] October 1980 (1980-10-01), SUGIMOTO Y ET AL: "Influence of chemical modification of N alpha-cocoyl-L-arginine ethyl ester on its hepatitis B surface antigen-inactivating effect.", XP002203217, Database accession no. NLM7447415
PEREZ, LOURDES ET AL.: "SYNTHESIS AGGREGATION AND BIOLOGICAL PROPERTIES OF A NEW CLASS OF GEMINI CATIONIC AMPHIPHILIC COMPOUNDS FROM ARGININE BIS(ARGS)", LANGMUIR (1996) 12(22) 5296-5301, XP002203216
HIROSHI NAKAMURA ET AL: "ANTIBACTERIAL ACTIVITY OF AMPHIPATHIC BASIC PEPTIDES WITH A LONG ACYL GROUP AND THEIR INTERACTION WITH PHOSPHOLIPID BILAYERS", BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, JAPAN PUBLICATIONS TRADING CO. TOKYO, JP, vol. 63, no. 4, 1 April 1990 (1990-04-01), pages 1180 - 1184, XP000127677, ISSN: 0009-2673
DATABASE MEDLINE [online] October 1980 (1980-10-01), SUGIMOTO Y ET AL: "Influence of chemical modification of N alpha-cocoyl-L-arginine ethyl ester on its hepatitis B surface antigen-inactivating effect.", XP002203217, Database accession no. NLM7447415
PEREZ, LOURDES ET AL.: "SYNTHESIS AGGREGATION AND BIOLOGICAL PROPERTIES OF A NEW CLASS OF GEMINI CATIONIC AMPHIPHILIC COMPOUNDS FROM ARGININE BIS(ARGS)", LANGMUIR (1996) 12(22) 5296-5301, XP002203216
HIROSHI NAKAMURA ET AL: "ANTIBACTERIAL ACTIVITY OF AMPHIPATHIC BASIC PEPTIDES WITH A LONG ACYL GROUP AND THEIR INTERACTION WITH PHOSPHOLIPID BILAYERS", BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, JAPAN PUBLICATIONS TRADING CO. TOKYO, JP, vol. 63, no. 4, 1 April 1990 (1990-04-01), pages 1180 - 1184, XP000127677, ISSN: 0009-2673
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