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Title:
CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREFOR
Document Type and Number:
WIPO Patent Application WO2001009094
Kind Code:
A3
Abstract:
Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by structural formula (XXIV) or Z-Y-(CH2)n-X-NR<50>R<5> and physiologically acceptable salts thereof.

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Inventors:
LULY JAY R (US)
NAKASATO YOSHISUKE (JP)
OHSHIMA ETSUO (JP)
SONE HIROKI (JP)
KOTERA OSAMU (JP)
HARRIMAN GERALDINE C B (US)
CARSON KENNETH G (US)
Application Number:
PCT/US2000/020607
Publication Date:
July 05, 2001
Filing Date:
July 28, 2000
Export Citation:
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Assignee:
MILLENNIUM PHARM INC (US)
KYOWA HAKKO KOGYO KK (JP)
LULY JAY R (US)
NAKASATO YOSHISUKE (JP)
OHSHIMA ETSUO (JP)
SONE HIROKI (JP)
KOTERA OSAMU (JP)
HARRIMAN GERALDINE C B (US)
CARSON KENNETH G (US)
International Classes:
A61P29/00; C07D211/52; C07D313/12; C07D401/06; C07D401/14; C07D405/06; C07D409/06; C07D471/04; C07D491/04; C07D493/04; C07D495/04; C07D519/00; (IPC1-7): C07D211/52; A61K31/4523; A61K31/497; A61P29/00; C07D313/12; C07D401/06; C07D401/14; C07D405/06; C07D409/06; C07D471/04; C07D491/04; C07D493/04; C07D495/04; C07D519/00
Domestic Patent References:
WO1998002151A21998-01-22
WO1999037619A11999-07-29
WO1999037617A11999-07-29
WO2000014089A12000-03-16
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