Title:
COMPOSITION CONTROLLING PHARMACOKINETICS IN THE BODY
Document Type and Number:
WIPO Patent Application WO/2019/176916
Kind Code:
A1
Abstract:
The present invention provides a composition that controls pharmacokinetics. Specifically, the present invention provides: a composition that is for controlling pharmacokinetics and that contains polyvalent cations as an active ingredient; and a method that controls pharmacokinetics by using polyvalent cations.
Inventors:
KATAOKA KAZUNORI (JP)
OSAWA SHIGEHITO (JP)
UCHIDA SATOSHI (JP)
HAYASHI KOTARO (JP)
DIRISALA ANJANEYULU (JP)
TOH KAZUKO (JP)
OSAWA SHIGEHITO (JP)
UCHIDA SATOSHI (JP)
HAYASHI KOTARO (JP)
DIRISALA ANJANEYULU (JP)
TOH KAZUKO (JP)
Application Number:
PCT/JP2019/009919
Publication Date:
September 19, 2019
Filing Date:
March 12, 2019
Export Citation:
Assignee:
KAWASAKI INST OF INDUSTRIAL PROMOTION (JP)
International Classes:
A61K47/34; A61K47/10
Domestic Patent References:
| WO2018038155A1 | 2018-03-01 | |||
| WO2016178431A1 | 2016-11-10 | |||
| WO2013162041A1 | 2013-10-31 | |||
| WO2015075942A1 | 2015-05-28 |
Foreign References:
| JP2017105802A | 2017-06-15 |
Other References:
MINCHIN, RODNEY F. ET AL.: "Polyinosinic Acid and Polycationic Liposomes Attenuate the Hepatic Clearance of Circulating Plasmid DNA", THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 296, 2001, pages 1006 - 1012, XP055636124
ZHENG, MENGYAO ET AL.: "Enhancing in vivo circulation and siRNA deli very with biodegradable polyethylenimine-graft-polycaprolactone-block- poly(ethylene glycol) copolymers", BIOMATERIALS, vol. 33, 2012, pages 6551 - 6558, XP028401114
OSAWA S. ET AL., BIOMACROMOLECULE, vol. 17, no. 1, 2016, pages 354 - 361
EUROPEAN POLYMER JOURNAL, vol. 88, 2017, pages 553 - 561
"Part A Polym. Chem.", J. POLYM. SCI., vol. 41, 2003, pages 1167 - 1187
BIOCONJUGATE, vol. 18, 2007, pages 2191 - 2196
BIOMATERIAL, vol. 126, 2017, pages 31 - 38
See also references of EP 3766519A4
ZHENG, MENGYAO ET AL.: "Enhancing in vivo circulation and siRNA deli very with biodegradable polyethylenimine-graft-polycaprolactone-block- poly(ethylene glycol) copolymers", BIOMATERIALS, vol. 33, 2012, pages 6551 - 6558, XP028401114
OSAWA S. ET AL., BIOMACROMOLECULE, vol. 17, no. 1, 2016, pages 354 - 361
EUROPEAN POLYMER JOURNAL, vol. 88, 2017, pages 553 - 561
"Part A Polym. Chem.", J. POLYM. SCI., vol. 41, 2003, pages 1167 - 1187
BIOCONJUGATE, vol. 18, 2007, pages 2191 - 2196
BIOMATERIAL, vol. 126, 2017, pages 31 - 38
See also references of EP 3766519A4
Attorney, Agent or Firm:
OHNO Seiji et al. (JP)
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