Title:
COMPOSITION FOR DENTIN ADHESION AND COMPOSITION FOR PULP RESTORATION, EACH COMPOSITION CONTAINING CPNE7-DERIVED PEPTIDE
Document Type and Number:
WIPO Patent Application WO/2024/058315
Kind Code:
A1
Abstract:
A dentin adhesion composition according to the present invention contains a peptide composed of the amino acid sequence of the following general formula 1: K-Y-R1-R2-R3-R4-R5-R6-R7-R8 (General formula 1), in general formula 1, R1 is arginine (R), lysine (K), or glutamine (Q); R2 is arginine (R) or glutamine (Q); R3, R4, and R5 are each arginine (R) or lysine (K); R6 is asparagine (N) or serine (S); and R7 and R8 are lysine (K) or tyrosine (Y). The composition according to the present invention is applied to the treatment of damaged dentin, such as dental caries or fractures, and thus can prevent possible dentin necrosis, dental extraction, or dental loss after treatment.
Inventors:
PARK JOO HWANG (KR)
GUG HYE RI (KR)
SHON WON JUN (KR)
GUG HYE RI (KR)
SHON WON JUN (KR)
Application Number:
PCT/KR2022/020540
Publication Date:
March 21, 2024
Filing Date:
December 16, 2022
Export Citation:
Assignee:
HYSENSBIO CO LTD (KR)
SEOUL NATIONAL UNIV DENTAL HOSPITAL (KR)
SEOUL NATIONAL UNIV DENTAL HOSPITAL (KR)
International Classes:
A61K6/884; C07K7/06
Foreign References:
| KR20180076996A | 2018-07-06 | |||
| KR20210152677A | 2021-12-16 | |||
| KR20150145470A | 2015-12-30 | |||
| KR20180076043A | 2018-07-05 |
Other References:
LEE YOON, PARK YEOUNG-HYUN, LEE DONG-SEOL, SEO YOU-MI, LEE JI-HYUN, PARK JOO-HWANG, CHOUNG HAN-WOOL, PARK SO-HYUN, SHON WON, PARK : "Tubular Dentin Regeneration Using a CPNE7-Derived Functional Peptide", MATERIALS, vol. 13, no. 20, 16 October 2020 (2020-10-16), pages 4618, XP093089559, DOI: 10.3390/ma13204618
Attorney, Agent or Firm:
HUH, Jung Hoon (KR)
Download PDF:
Previous Patent: ICE TANGHULU AND MANUFACTURING METHOD THEREFOR
Next Patent: PRODUCT-PACKING AUTOMATION SYSTEM AND METHOD
Next Patent: PRODUCT-PACKING AUTOMATION SYSTEM AND METHOD