Title:
COMPOSITION FOR IMMUNOSUPPRESSION COMPRISING L-AHG
Document Type and Number:
WIPO Patent Application WO/2024/034735
Kind Code:
A1
Abstract:
The present invention relates to a composition for immunosuppression comprising 3,6-anhydro-L-galactose (L-AHG) as an active ingredient, and to a pharmaceutical composition, functional health food, and functional cosmetic composition comprising the active ingredient for preventing or treating immune diseases. The composition for immunosuppression comprising L-AHG, the pharmaceutical composition, and the functional health food and functional cosmetic composition of the present invention have the excellent effect of selectively and effectively inhibiting the activation, proliferation, and differentiation of CD4 T cells, which are the main target of an immunosuppressive agent, and thus, the present invention is very useful for the pharmaceutical, food, and cosmetic industries.
Inventors:
KIM YOUNG HO (KR)
PARK SHIN YOUNG (KR)
JANG WON YOUNG (KR)
PARK SHIN YOUNG (KR)
JANG WON YOUNG (KR)
Application Number:
PCT/KR2022/017595
Publication Date:
February 15, 2024
Filing Date:
November 09, 2022
Export Citation:
Assignee:
KYUNGPOOK NAT UNIV IND ACADEMIC COOP FOUND (KR)
International Classes:
A61K31/7004; A23L33/125; A61K8/60; A61P37/00; A61P37/06; A61Q19/00
Foreign References:
| KR20130085017A | 2013-07-26 | |||
| KR20190061899A | 2019-06-05 | |||
| KR20220074403A | 2022-06-03 | |||
| KR20140113122A | 2014-09-24 |
Other References:
LEE JAE-EUN; KIM YOUNG-AH; YU SORA; PARK SO YOUNG; KIM KYOUNG HEON; KANG NAM JOO: "3,6-Anhydro-L-galactose increases hyaluronic acid production via the EGFR and AMPKα signaling pathway in HaCaT keratinocytes", JOURNAL OF DERMATOLOGICAL SCIENCE, ELSEVIER, AMSTERDAM, NL, vol. 96, no. 2, 1 November 2019 (2019-11-01), AMSTERDAM, NL , pages 90 - 98, XP085946216, ISSN: 0923-1811, DOI: 10.1016/j.jdermsci.2019.10.005
PATHIRAJA DULEEPA, LEE SAEYOUNG, CHOI IN-GEOL: "Model-based complete enzymatic production of 3,6-Anhydro-l-galactose from red algal biomass", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 66, no. 26, 5 July 2018 (2018-07-05), US , pages 6814 - 6821, XP093139057, ISSN: 0021-8561, DOI: 10.1021/acs.jafc.8b01792
PATHIRAJA DULEEPA, LEE SAEYOUNG, CHOI IN-GEOL: "Model-based complete enzymatic production of 3,6-Anhydro-l-galactose from red algal biomass", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 66, no. 26, 5 July 2018 (2018-07-05), US , pages 6814 - 6821, XP093139057, ISSN: 0021-8561, DOI: 10.1021/acs.jafc.8b01792
Attorney, Agent or Firm:
SUH, Jang-Chan et al. (KR)
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