Title:
COMPOSITION FOR MEDICAL USE CONTAINING SUGAR CHAIN-CONTAINING CHITOSAN DERIVATIVE AND GLYCOSAMINOGLYCAN
Document Type and Number:
WIPO Patent Application WO/2005/025538
Kind Code:
A1
Abstract:
It is intended to provide a composition for medical use which has effects of positively promoting healing of an intractable wound and promoting angiogenesis and tissue regeneration while showing no risk of side effects such as cancerization. Namely, a composition for medical use characterized by comprising a hydrogel, which is formed by a sugar chain-containing chitosan derivative and an acidic polysaccharide, and a drug for promoting wound healing carried thereon. It is preferable that the sugar chain-containing chitosan derivative is one in which a saccharide having a reducing end is introduced at least a part of amino groups in the chitosan skeleton. It is preferable that the acidic polysaccharide is a glycosaminoglycan such as periodiate-oxidized heparin. It is preferable that the drug for promoting wound healing is a cell growth factor.
Inventors:
ISHIHARA MASAYUKI (JP)
YURA HIROFUMI (JP)
SAITO YOSHIO (JP)
OBARA KIYOHAYA (JP)
FUJITA MASANORI (JP)
YURA HIROFUMI (JP)
SAITO YOSHIO (JP)
OBARA KIYOHAYA (JP)
FUJITA MASANORI (JP)
Application Number:
PCT/JP2004/013042
Publication Date:
March 24, 2005
Filing Date:
September 08, 2004
Export Citation:
Assignee:
NETECH INC (JP)
ISHIHARA MASAYUKI (JP)
YURA HIROFUMI (JP)
SAITO YOSHIO (JP)
OBARA KIYOHAYA (JP)
FUJITA MASANORI (JP)
ISHIHARA MASAYUKI (JP)
YURA HIROFUMI (JP)
SAITO YOSHIO (JP)
OBARA KIYOHAYA (JP)
FUJITA MASANORI (JP)
International Classes:
A61K31/727; A61K38/18; A61K45/06; A61L26/00; A61P17/02; C12N5/07; C12N5/077; C12N5/09; (IPC1-7): A61K9/08; A61K47/36; A61K45/00; A61K38/17; A61K47/42; A61P17/02; A61L27/00; C12N5/08
Domestic Patent References:
| WO2000027889A1 | 2000-05-18 |
Foreign References:
| JPH10502665A | 1998-03-10 | |||
| JP2002136588A | 2002-05-14 | |||
| JP2000116765A | 2000-04-25 | |||
| JP2000186048A | 2000-07-04 | |||
| JPS5684701A | 1981-07-10 | |||
| JPH02112A | 1990-01-05 |
Attorney, Agent or Firm:
Okuhara, Koji (401 Shibasaki Dragon 1st Bldg., 2-9-25, Shibasaki-ch, Tachikawa-shi Tokyo 23, JP)
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