Title:
COMPOSITION FOR PREVENTING OR TREATING BONE DISEASES COMPRISING MUSSEL PROTEIN-DERIVED PEPTIDE AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2018/147516
Kind Code:
A1
Abstract:
The present invention relates to an osteogenic promotion peptide comprising sequence number 1 (PIISVYWK) or sequence number 2 (FSVVPSPK), and a composition, for preventing or treating bone diseases, comprising the peptide. The peptide promotes osteoblast differentiation and thus can be utilized for a bone disease treatment.
Inventors:
JE JAE-YOUNG (KR)
HYUNG JUN-HO (KR)
OH YUN-OK (KR)
HYUNG JUN-HO (KR)
OH YUN-OK (KR)
Application Number:
PCT/KR2017/008035
Publication Date:
August 16, 2018
Filing Date:
July 26, 2017
Export Citation:
Assignee:
NAT UNIV PUKYONG IND UNIV COOP FOUND (KR)
International Classes:
C07K7/06; A61K38/08; C12N5/077
Foreign References:
| KR20120049043A | 2012-05-16 | |||
| KR20040074025A | 2004-08-21 | |||
| US20040162415A1 | 2004-08-19 |
Other References:
PARK, S. Y. ET AL.: "Partial Purification and Identification of Three Antioxidant Peptides with Hepatoprotective Effects from Blue Mussel (Mytilus edulis) Hydrolysate by Peptic Hydrolysis", JOURNAL OF FUNCTIONAL FOODS, vol. 20, 10 November 2015 (2015-11-10), pages 88 - 95, XP029360118
POUNTOS, I. ET AL.: "The Rote of Peptides in Bone Healing and Regeneration: a Systematic Review", BIOMED CENTRAL MEDICINE, vol. 14, no. 103, 2016, pages 1 - 15, XP055534428
JE, J-Y. ET AL.: "Blue Mussel-derived Antioxidant Peptides PIIVYWK and FSVVPSPK Exert Osteogenic Activities in Mouse Mesenchymal Stem Cells via MAPK-dependent BMP Signaling Pathway", FOOD SCIENCE FOR DAILY LIVING VIA INNOVATION AND CONVERGENCE, 17 August 2016 (2016-08-17), Korea
JE, JAE-YOUNG ET AL.: "Blue Mussel-derived Antioxidant Peptides PIIVYWK and FSVVPSPK Exert Osteogenic Activities in Mouse Mesenchymal Stem Cells via MAPK-dependent BMP Signaling Pathway", IN: 2016 THE KOREAN SOCIETY OF INDUSTRIAL AND ENGINEERING CHEMISTRY(KSIEC) FALL MEETING AND CONFERENCE, 26 October 2016 (2016-10-26), Korea
HYUNG, J-H . ET AL.: "Blue Mussel-derived Antioxidant Peptides PIIVYWK and FSVVPSPK Exert Osteogenic Activities in Mouse Mesenchymal Stem Cells via MAPK-dependent BMP Signaling Pathway", IN: FOOD AND NUTRITION FOR FUTURE: GLOCALIZATION TO TECHNOLOGY BREAKTHROUGH , 2016 KFN INTERNATIONAL SYMPOSIUM AND ANNUAL MEETING, Korea
POUNTOS, I. ET AL.: "The Rote of Peptides in Bone Healing and Regeneration: a Systematic Review", BIOMED CENTRAL MEDICINE, vol. 14, no. 103, 2016, pages 1 - 15, XP055534428
JE, J-Y. ET AL.: "Blue Mussel-derived Antioxidant Peptides PIIVYWK and FSVVPSPK Exert Osteogenic Activities in Mouse Mesenchymal Stem Cells via MAPK-dependent BMP Signaling Pathway", FOOD SCIENCE FOR DAILY LIVING VIA INNOVATION AND CONVERGENCE, 17 August 2016 (2016-08-17), Korea
JE, JAE-YOUNG ET AL.: "Blue Mussel-derived Antioxidant Peptides PIIVYWK and FSVVPSPK Exert Osteogenic Activities in Mouse Mesenchymal Stem Cells via MAPK-dependent BMP Signaling Pathway", IN: 2016 THE KOREAN SOCIETY OF INDUSTRIAL AND ENGINEERING CHEMISTRY(KSIEC) FALL MEETING AND CONFERENCE, 26 October 2016 (2016-10-26), Korea
HYUNG, J-H . ET AL.: "Blue Mussel-derived Antioxidant Peptides PIIVYWK and FSVVPSPK Exert Osteogenic Activities in Mouse Mesenchymal Stem Cells via MAPK-dependent BMP Signaling Pathway", IN: FOOD AND NUTRITION FOR FUTURE: GLOCALIZATION TO TECHNOLOGY BREAKTHROUGH , 2016 KFN INTERNATIONAL SYMPOSIUM AND ANNUAL MEETING, Korea
Attorney, Agent or Firm:
WIE, Byoung-Gap (KR)
Download PDF: