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Title:
COMPOSITION FOR PROMOTING MEMORY AND PREVENTING, ALLEVIATING OR TREATING COGNITIVE IMPAIRMENT, CONTAINING YUK-GUNJA-TANG AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2023/249280
Kind Code:
A1
Abstract:
The present invention relates to a composition for promoting memory and preventing, alleviating or treating cognitive impairment, containing Yuk-Gunja-Tang as an active ingredient. Specifically, Yuk-Gunja-Tang, which is prepared by putting a mixture of Panax ginseng, Atractylodis Rhizoma Alba, Poria cocos, Glycyrrhizae Radix et Rhizoma, Citri Unshius Pericarpium, Pinellia ternata, Zingiberis Rhizoma Recens and Zizyphi Fructus in water and boiling same, has neuroprotective effects superior to those of individual extracts of each of Panax ginseng, Atractylodis rhizoma alba, Poria cocos, Glycyrrhizae Radix et Rhizoma, Citri Unshius Pericarpium, Pinellia ternata, Zingiberis Rhizoma Recens and Zizyphi Fructus, and exhibits effects of improving memory and cognitive function when administered to an animal model with scopolamine-induced cognitive decline, and thus can be effectively used as a food, a drug and the like for prevention or treatment of brain diseases including Alzheimer's disease, Parkinson's disease, mild cognitive impairment and the like.

Inventors:
PAK MALK EUN (KR)
GO YOUNGHOON (KR)
LI WEI (KR)
YANG HYE JIN (KR)
Application Number:
PCT/KR2023/007407
Publication Date:
December 28, 2023
Filing Date:
May 31, 2023
Export Citation:
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Assignee:
KOREA INST ORIENTAL MEDICINE (KR)
International Classes:
A23L33/105; A23K10/30; A61K36/076; A61K36/258; A61K36/284; A61K36/484; A61K36/725; A61K36/752; A61K36/8888; A61K36/9068
Foreign References:
KR20050035906A2005-04-20
KR20020066173A2002-08-14
KR20210148802A2021-12-08
KR20020096925A2002-12-31
Other References:
CHOI YUJIN, KIM AE-RAN, LEE JI-YOON, KIM HAE SOOK, YANG CHANGSOP, KIM JAE KWANG, GO YOUNGHOON, JUNG IN CHUL: "Herbal Medicine for Patients with Cognitive Impairment: An Observational Study", NEUROPSYCHIATRIC DISEASE AND TREATMENT, vol. Volume 17, pages 3183 - 3194, XP093120858, ISSN: 1178-2021, DOI: 10.2147/NDT.S333569
Attorney, Agent or Firm:
CHOI, Kyu Whan (KR)
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