Title:
COMPOSITION FOR SYMPATHETIC NERVE ACTIVATION
Document Type and Number:
WIPO Patent Application WO/2021/059755
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a technique that enables sympathetic nerve activation. A composition for sympathetic nerve activation, said composition containing one or more peptides selected from the group consisting of peptides consisting of any of the following amino acid sequences (SEQ ID NOS: 1-16) and peptides containing these amino acid sequences. (Amino acid sequences: VAPFPE, HLPLP, VVPPF, HQPHQPLPPT, TEDELQDK, LNPWDQ, IISQE, ANEEEY, VIPY, LPLP, VIESPPEIN, FPQY, LNVPGE, IVPNSAEE, GEPTSTPT and KFQSEEQQQ)
Inventors:
YAGO TAKUMI (JP)
SAKATA YASUYUKI (JP)
SAITO NORIKO (JP)
SAKATA YASUYUKI (JP)
SAITO NORIKO (JP)
Application Number:
PCT/JP2020/029893
Publication Date:
April 01, 2021
Filing Date:
August 04, 2020
Export Citation:
Assignee:
MORINAGA MILK INDUSTRY CO LTD (JP)
International Classes:
A61K38/17; A61K35/20; A61K38/07; A61P3/00; A61P3/04; A61P25/02; A61P25/26; C07K5/103; C07K5/107; C07K14/47
Domestic Patent References:
| WO2019058609A1 | 2019-03-28 |
Foreign References:
| JP2005239579A | 2005-09-08 | |||
| JP2016065038A | 2016-04-28 |
Other References:
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TU, MAOLIN, LIU HANXIONG, ZHANG RUYI, CHEN HUI, FAN FENGJIAO, SHI PUJIE, XU XIANBING, LU WEIHONG, DU MING: "Bioactive hydrolysates from casein: generation, identification, and in silico toxicity and allergenicity prediction of peptides", JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, vol. 98, no. 9, 2018, pages 3416 - 3426, XP055807064, ISSN: 0022-5142, DOI: 10.1002/jsfa.8854
MINAKASOHI, YASUHIKO: "Regulatory role of hypothalamus-sympathetic nervous system in energy metabolism", JOURNAL OF JAPAN SOCIETY FOR THE STUDY OF OBESITY, vol. 5, no. 3, 30 November 1998 (1998-11-30), JP , pages 15 (169) - 22 (176), XP009535451, ISSN: 1343-229X
OKUMURA NOBUAKI: "Bioenergy consumption system and regulatory mechanism Metabolic regulation by the autonomic nervous system. 2. Autonomic nerves and energy consumption", JAPANESE JOURNAL OF CLINICAL MEDICINE, vol. 61, no. special issue 6, 30 November 2002 (2002-11-30), JP , pages 259 - 264, XP009535453, ISSN: 0047-1852
MATSUNAGA, YUTAKA, YASUYUKI SAKATA, TAKUMI YAGO, HIROHIKO NAKAMURA, TAKASHI SHIMIZU AND YASUHIRO TAKEDA: "Effects of glucose with casein peptide supplementation on post-exercise muscle glycogen resynthesis in C57BL/6JMice", NUTRIENTS, vol. 10, no. 6, 2018, pages 753, XP055807155, ISSN: 2072-6643, DOI: 10.3390/nul0060753
LILLEFOSSE, H. H. ET AL.: "Hydrolyzed casein reduces diet-induced obesity in male C57BL/6J mice", THE JOURNAL OF NUTRITION, vol. 143, no. 9, 2013, pages 1367 - 1375, XP055585024, ISSN: 0022-3166, DOI: 10.3945/jn.112.170415
DULOOO AG. ET AL., AM. J. CLIN. NUTR., vol. 49, no. 1, 1989, pages 44 - 50
TAKASHI ANDO, PHYSICAL FITNESS SCIENCE, vol. 67, no. 5, 2018, pages 327 - 344
TADAISHI ET AL., PLOS ONE., vol. 6, no. 12, 2011, pages e28290
P. DIAMOND ET AL., AM. J. PHYSIOL., vol. 252, no. 6, June 1987 (1987-06-01), pages E719 - 26
Y. TAKAHASHI ET AL., J. PHYS. FITNESS SPORTS MED., vol. 2, no. 3, 2013, pages 373 - 379
TU, MAOLIN, LIU HANXIONG, ZHANG RUYI, CHEN HUI, FAN FENGJIAO, SHI PUJIE, XU XIANBING, LU WEIHONG, DU MING: "Bioactive hydrolysates from casein: generation, identification, and in silico toxicity and allergenicity prediction of peptides", JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, vol. 98, no. 9, 2018, pages 3416 - 3426, XP055807064, ISSN: 0022-5142, DOI: 10.1002/jsfa.8854
MINAKASOHI, YASUHIKO: "Regulatory role of hypothalamus-sympathetic nervous system in energy metabolism", JOURNAL OF JAPAN SOCIETY FOR THE STUDY OF OBESITY, vol. 5, no. 3, 30 November 1998 (1998-11-30), JP , pages 15 (169) - 22 (176), XP009535451, ISSN: 1343-229X
OKUMURA NOBUAKI: "Bioenergy consumption system and regulatory mechanism Metabolic regulation by the autonomic nervous system. 2. Autonomic nerves and energy consumption", JAPANESE JOURNAL OF CLINICAL MEDICINE, vol. 61, no. special issue 6, 30 November 2002 (2002-11-30), JP , pages 259 - 264, XP009535453, ISSN: 0047-1852
MATSUNAGA, YUTAKA, YASUYUKI SAKATA, TAKUMI YAGO, HIROHIKO NAKAMURA, TAKASHI SHIMIZU AND YASUHIRO TAKEDA: "Effects of glucose with casein peptide supplementation on post-exercise muscle glycogen resynthesis in C57BL/6JMice", NUTRIENTS, vol. 10, no. 6, 2018, pages 753, XP055807155, ISSN: 2072-6643, DOI: 10.3390/nul0060753
LILLEFOSSE, H. H. ET AL.: "Hydrolyzed casein reduces diet-induced obesity in male C57BL/6J mice", THE JOURNAL OF NUTRITION, vol. 143, no. 9, 2013, pages 1367 - 1375, XP055585024, ISSN: 0022-3166, DOI: 10.3945/jn.112.170415
DULOOO AG. ET AL., AM. J. CLIN. NUTR., vol. 49, no. 1, 1989, pages 44 - 50
TAKASHI ANDO, PHYSICAL FITNESS SCIENCE, vol. 67, no. 5, 2018, pages 327 - 344
TADAISHI ET AL., PLOS ONE., vol. 6, no. 12, 2011, pages e28290
P. DIAMOND ET AL., AM. J. PHYSIOL., vol. 252, no. 6, June 1987 (1987-06-01), pages E719 - 26
Y. TAKAHASHI ET AL., J. PHYS. FITNESS SPORTS MED., vol. 2, no. 3, 2013, pages 373 - 379
Attorney, Agent or Firm:
IP FIRM SHUWA (JP)
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