Title:
COMPOSITIONS DISINTEGRATING IN ORAL CAVITY AND PREPARATIONS DISINTEGRATING IN ORAL CAVITY
Document Type and Number:
WIPO Patent Application WO/2001/076565
Kind Code:
A1
Abstract:
Compositions quickly disintegrating in the oral cavity which contain a filler comprising a sugar alcohol, a disintegrating agent and a lubricant. The penetration rate of ethanol into this lubricant is 3.0 x 10?-3¿g?2¿/sec or above. The tablet strength is 20 N or above. The compositions disintegrate in the oral cavity of normal adults within 90 seconds. Preparations disintegrating in the oral cavity which are prepared by adding drug components to these compositions disintegrating in the oral cavity. Thus, both of an appropriate strength needed in handling the preparations and quick disintegration in the oral cavity can be achieved without resort to any special production procedures or instruments.
Inventors:
NARUSHIMA MAKOTO (JP)
AIZAWA KAZUTOSHI (JP)
SHIMOYAMA HIROYASU (JP)
ISHIKAWA KIYOFUMI (JP)
AIZAWA KAZUTOSHI (JP)
SHIMOYAMA HIROYASU (JP)
ISHIKAWA KIYOFUMI (JP)
Application Number:
PCT/JP2001/003114
Publication Date:
October 18, 2001
Filing Date:
April 11, 2001
Export Citation:
Assignee:
BANYU PHARMA CO LTD (JP)
NARUSHIMA MAKOTO (JP)
AIZAWA KAZUTOSHI (JP)
SHIMOYAMA HIROYASU (JP)
ISHIKAWA KIYOFUMI (JP)
NARUSHIMA MAKOTO (JP)
AIZAWA KAZUTOSHI (JP)
SHIMOYAMA HIROYASU (JP)
ISHIKAWA KIYOFUMI (JP)
International Classes:
A61K9/00; A61K47/04; (IPC1-7): A61K9/20; A61K45/00; A61K47/04; A61K47/12; A61K47/18; A61K47/26; A61K47/36; A61K47/38; A61K47/44; A61P1/00; A61P3/02; A61P5/00; A61P7/00; A61P9/00; A61P11/00; A61P15/00; A61P25/00; A61P27/00; A61P33/00; A61P35/00; A61P37/08; A61P43/00
Foreign References:
| JPH09194381A | 1997-07-29 | |||
| JPH10287555A | 1998-10-27 | |||
| JPH03227916A | 1991-10-08 | |||
| JP2000178182A | 2000-06-27 |
Attorney, Agent or Firm:
Matoba, Motonori c/o Matoba International Patent Office MR Building 3F 30-17 (Hongo 1-chome Bunkyo-ku, Tokyo, JP)
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