COMPOSITIONS AND METHODS FOR INHIBITING BONE RESORPTION

Title:

COMPOSITIONS AND METHODS FOR INHIBITING BONE RESORPTION

Document Type and Number:

WIPO Patent Application WO1999067809

Kind Code:

A9

Abstract:

The present invention relates to oral compositions and methods for inhibiting bone resoprtion in a mammal while counteracting the occurrence of potentially adverse gastrointestinal effects. The compositions useful herein comprise the combination of a pharmaceutically effective amount of a nitrogen-containing bisphosphonate or a pharmaceutically-acceptable salt thereof and a pharmaceutically effective amount of an isoprenoid compound.

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Inventors:

RESZKA ALFRED A (US)
SCOLNICK EDWARD M (US)

Application Number:

PCT/US1999/013967

Publication Date:

March 22, 2001

Filing Date:

June 21, 1999

Export Citation:

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Assignee:

MERCK & CO INC (US)
RESZKA ALFRED A (US)
SCOLNICK EDWARD M (US)

International Classes:

A61K31/01; A61K31/045; A61K31/075; A61K31/133; A61K31/22; A61K31/66; A61K31/663; A61K31/675; A61P19/10; A61P43/00; (IPC1-7): A61K31/66; A61K31/01

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