Title:
COMPOUND CONTAINING BENZYL STRUCTURE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/155879
Kind Code:
A1
Abstract:
The present invention discloses a compound containing a benzyl structure and a use thereof. The compound containing a benzyl structure of the present invention contains a hydroxyl, an amino group, a substituted amino group, and an active group, and can be used as an amino acid or a peptide C-terminal protection reagent. A peptide synthesis reaction using this protection carrier has a fast reaction speed and a high reagent utilization rate in a suitable solvent system; effective purification can be carried out when post-treatment is carried out by means of simple liquid-liquid extraction separation, and finally, a product with a high purity can be obtained; and during a synthesis process, the change in solubility is small and an operation process has a strong universality, and therefore a universal production method can be developed.
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Inventors:
ZHENG QINGQUAN (CN)
LIANG WEIZHOU (CN)
TANG QI (CN)
LIANG WEIZHOU (CN)
TANG QI (CN)
Application Number:
PCT/CN2019/125132
Publication Date:
August 06, 2020
Filing Date:
December 13, 2019
Export Citation:
Assignee:
GUANGZHOU TROJAN PHARMATEC LTD (CN)
International Classes:
C07C235/48; C07K1/04; C07K1/06
Domestic Patent References:
| WO1992007850A1 | 1992-05-14 |
Foreign References:
| CN110183347A | 2019-08-30 | |||
| CN104906592A | 2015-09-16 | |||
| CN106220482A | 2016-12-14 |
Other References:
ALLAN WISSNER , MARION L CARROLL , BERNARD D JOHNSON , SURESH S KEWAR , WALTER C PICKETT , ROBERT E SCHAUB , LAWRENCE W TORLEY , M: "Analogs of Platelet Activating Factor. 7. Bis-Aryl Amide and Bis-Aryl Urea Receptor Antagonists of PAF", JOURNAL OF MEDICINAL CHEMISTRY, vol. 35, no. 26, 25 December 1992 (1992-12-25), pages 4779 - 4789, XP000676688, ISSN: 0022-2623, DOI: 10.1021/jm00104a002
Attorney, Agent or Firm:
JIAQUAN IP LAW FIRM (CN)
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