Title:
COMPOUND, AND LABELED BIOLOGICAL SUBSTANCE IN WHICH SAME IS USED
Document Type and Number:
WIPO Patent Application WO/2022/025210
Kind Code:
A1
Abstract:
A compound of the following formula, and a labeled biological substance having the compound. R1 to R6, R11 to R13, and R22 to R29 respectively represent specific groups, and n represents an integer of 1 to 3. One group selected from R1, R2, R5, and R22 to R25 and one group selected from R3, R4, R6, and R26 to R29 are bonded to each other through a linking group LL. The linking group LL represents a linking group that has 1 to 100 atoms and does not have either one of an aromatic hydrocarbon ring, a sulfo group or a phosphono group. At least one of R1 to R6, and R22 to R29 contains a structure represented by -(CH2-CH2-O)m- in which m = 1 to 50. The compound is a neutral compound and contains at least one substituent capable of binding to a carboxyl group or a biological substance.
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Inventors:
KANAZAWA YOSHINORI (JP)
FUJIWARA RYO (JP)
KOMIYAMA KAZUOKI (JP)
FUJIWARA RYO (JP)
KOMIYAMA KAZUOKI (JP)
Application Number:
PCT/JP2021/028180
Publication Date:
February 03, 2022
Filing Date:
July 29, 2021
Export Citation:
Assignee:
FUJIFILM CORP (JP)
International Classes:
C07K1/13; C09B23/01; C09B23/02; G01N33/533; G01N33/58
Domestic Patent References:
| WO2001002374A1 | 2001-01-11 | |||
| WO2005000218A2 | 2005-01-06 | |||
| WO2006047452A2 | 2006-05-04 | |||
| WO2012012595A2 | 2012-01-26 | |||
| WO2002026891A1 | 2002-04-04 | |||
| WO2001002374A1 | 2001-01-11 |
Foreign References:
| US20130230466A1 | 2013-09-05 | |||
| US20150073154A1 | 2015-03-12 | |||
| JP2011506673A | 2011-03-03 | |||
| JP2013539015A | 2013-10-17 | |||
| JPH0847400A | 1996-02-20 | |||
| JP2020129754A | 2020-08-27 |
Other References:
EWA WOLINSKA, MAGED HENARY, EKATERINA PALIAKOV, LUCJAN STREKOWSKI: "Near-infrared bis(indolium heptamethine cyanine) dyes with a spacer derived from oligo(ethylene glycol)", JOURNAL OF HETEROCYCLIC CHEMISTRY, vol. 46, no. 5, 1 September 2009 (2009-09-01), US , pages 925 - 930, XP055305406, ISSN: 0022-152X, DOI: 10.1002/jhet.171
LUCAS C. D. DE REZENDEFLAVIO DA SILVA EMERY: "A Review of the Synthetic Strategies for the Development of BODIPY Dyes for Conjugation with Proteins", ORBITAL: THE ELECTRONIC JOURNAL OF CHEMISTRY, vol. 5, no. 1, 2013, pages 62 - 83, XP055974577
LUCAS C. D. DE REZENDEFLAVIO DA SILVA EMERY: "A Review of the Synthetic Strategies for the Development of BODIPY Dyes for Conjugation with Proteins", ORBITAL: THE ELECTRONIC JOURNAL OF CHEMISTRY, vol. 5, no. 1, 2013, pages 62 - 83, XP055974577
Attorney, Agent or Firm:
IIDA & PARTNERS et al. (JP)
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