Title:
COMPOUNDS FOR NONSENSE SUPPRESSION, USE OF THESE COMPOUNDS FOR THE MANUFACTURE OF A MEDICAMENT FOR TREATING SOMATIC MUTATION-RELATED DISEASES
Document Type and Number:
WIPO Patent Application WO2006044503
Kind Code:
A3
Abstract:
The present invention relates to compounds, compositions and their use for the manfacture of midicament for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or compositions of the present invention. More particularly, the present invention relates to methods, compounds, and compositions for suppressing premature translation termination associated with a nonsense mutation in an mRNA.
Inventors:
WILDE RICHARD (US)
WELCH ELLEN (US)
KARP GARY M (US)
WELCH ELLEN (US)
KARP GARY M (US)
Application Number:
PCT/US2005/036762
Publication Date:
July 06, 2006
Filing Date:
October 13, 2005
Export Citation:
Assignee:
PTC THERAPEUTICS INC (US)
WILDE RICHARD (US)
WELCH ELLEN (US)
KARP GARY M (US)
WILDE RICHARD (US)
WELCH ELLEN (US)
KARP GARY M (US)
International Classes:
A61K47/08; A61K31/423; A61K31/424; A61K31/4245; A61K47/16; A61P35/00
Domestic Patent References:
| WO2002036580A2 | 2002-05-10 | |||
| WO2004046122A2 | 2004-06-03 | |||
| WO1999059586A1 | 1999-11-25 | |||
| WO1998023611A1 | 1998-06-04 |
Foreign References:
| US20020107269A1 | 2002-08-08 |
Other References:
DELUCA M R ET AL: "The Total Synthesis of UK-1", 13 January 1997, TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, NL, PAGE(S) 199-202, ISSN: 0040-4039, XP004070502
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