Title:
COMPREHENSIVE GLAUCOMA DETERMINATION METHOD UTILIZING GLAUCOMA DIAGNOSIS CHIP AND DEFORMED PROTEOMICS CLUSTER ANALYSIS
Document Type and Number:
WIPO Patent Application WO/2012/091093
Kind Code:
A1
Abstract:
Provided is a technique for determining a physiological attribute in a mammal, including the onset or progression of human glaucoma, with high accuracy. The results of the determination of genotype date and the results of the determination of cytokine date are consolidated by a consolidated determination unit (114),;comparison is made for determining as to which is larger, the number of Case determination procedures or the number of Control determination procedures (S330); and it is determined as Case (glaucoma) when the number of Case determination procedures is larger and it is determined as Control (normal person) when the number of Control determination procedures is larger.
Inventors:
TASHIRO KEI (JP)
KINOSHITA SHIGERU (JP)
YAGI TOMOHITO (JP)
NAKANO MASAKAZU (JP)
MORI KAZUHIKO (JP)
IKEDA YOKO (JP)
UENO MORIO (JP)
TOKUDA YUICHI (JP)
YAGI KATSUMI (JP)
YOSHII KENGO (JP)
FUWA MASAHIRO (JP)
KINOSHITA SHIGERU (JP)
YAGI TOMOHITO (JP)
NAKANO MASAKAZU (JP)
MORI KAZUHIKO (JP)
IKEDA YOKO (JP)
UENO MORIO (JP)
TOKUDA YUICHI (JP)
YAGI KATSUMI (JP)
YOSHII KENGO (JP)
FUWA MASAHIRO (JP)
Application Number:
PCT/JP2011/080393
Publication Date:
July 05, 2012
Filing Date:
December 28, 2011
Export Citation:
Assignee:
TASHIRO KEI (JP)
KINOSHITA SHIGERU (JP)
SANTEN PHARMACEUTICAL CO LTD (JP)
YAGI TOMOHITO (JP)
NAKANO MASAKAZU (JP)
MORI KAZUHIKO (JP)
IKEDA YOKO (JP)
UENO MORIO (JP)
TOKUDA YUICHI (JP)
YAGI KATSUMI (JP)
YOSHII KENGO (JP)
FUWA MASAHIRO (JP)
KINOSHITA SHIGERU (JP)
SANTEN PHARMACEUTICAL CO LTD (JP)
YAGI TOMOHITO (JP)
NAKANO MASAKAZU (JP)
MORI KAZUHIKO (JP)
IKEDA YOKO (JP)
UENO MORIO (JP)
TOKUDA YUICHI (JP)
YAGI KATSUMI (JP)
YOSHII KENGO (JP)
FUWA MASAHIRO (JP)
International Classes:
C12M1/00; G16H50/20; C12Q1/68; G06N3/00; G16B20/20; G16B20/40; G16B25/10; G16B40/20; G16B40/30
Foreign References:
| JP2003529131A | 2003-09-30 | |||
| JP2003500766A | 2003-01-07 | |||
| JP2003529561A | 2003-10-07 |
Other References:
IKUMITSU NAGASAKI: "Togoteki Shindan Algorithm Kaihatsu ni Kansuru Kenkyu, Ryokunaisho Shindan SNP Chip to Henkei Proteomics Cluster Kaiseki ni yoru Ryokunaisho Togoteki Shindanho no Kaihatsu ni Kansuru Kenkyu", HEISEI 20 NENDO SOKATSU BUNTAN KENKYU NENDO SHURYO HOKOKUSHO, 2009, pages 30 - 32, XP008170060
NAKANO M. ET AL.: "Three susceptible loci associated with primary open-angle glaucoma identified by genome-wide association study in a Japanese population", PNAS, vol. 106, no. 31, 2009, pages 12838 - 12842, XP055119766
See also references of EP 2660310A4
NAKANO M. ET AL.: "Three susceptible loci associated with primary open-angle glaucoma identified by genome-wide association study in a Japanese population", PNAS, vol. 106, no. 31, 2009, pages 12838 - 12842, XP055119766
See also references of EP 2660310A4
Attorney, Agent or Firm:
SK INTELLECTUAL PROPERTY LAW FIRM et al. (JP)
SK patent business corporation (JP)
SK patent business corporation (JP)
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