Title:
CONSTRUCTION OF CHIMERA USING ES CELLS
Document Type and Number:
WIPO Patent Application WO/2006/009297
Kind Code:
A1
Abstract:
It is intended to provide a chimeric animal which produces proteins and tissues of animals of the same or different species or in which desired multipotent cells are transmitted in the germ line and a multipotent cell lacking a specific gene and thus losing a function in which the gene participates. A method of constructing a chimeric animal which comprises injecting cells of two or more types containing a multipotent cell having the defect or mutation of a specific gene and thus losing a function in which the gene participates and another multipotent cell other than the above-described multipotent cell into an animal host embryo, and a chimeric animal constructed by this method.
Inventors:
NAGAO YASUMITSU (JP)
HORII TAKURO (JP)
HORII TAKURO (JP)
Application Number:
PCT/JP2005/013685
Publication Date:
January 26, 2006
Filing Date:
July 20, 2005
Export Citation:
Assignee:
NAGAO YASUMITSU (JP)
HORII TAKURO (JP)
HORII TAKURO (JP)
International Classes:
A01K67/027; C12N5/10; C12N15/873; C12P21/02
Domestic Patent References:
WO2003089580A2 | 2003-10-30 | |||
WO2003072777A1 | 2003-09-04 |
Foreign References:
JP2001299141A | 2001-10-30 | |||
JP2004503215A | 2004-02-05 | |||
JP2004166696A | 2004-06-17 |
Other References:
See also references of EP 1779724A4
Attorney, Agent or Firm:
Hiraki, Yusuke (3-20 Toranomon 4-chom, Minato-ku Tokyo 01, JP)
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