Title:
CRYPTOTANSHINONE DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN LOWERING LIPID AND RESISTING OBESITY
Document Type and Number:
WIPO Patent Application WO/2022/257995
Kind Code:
A1
Abstract:
Disclosed are a cryptotanshinone derivative and a preparation method therefor and an application thereof in lowering lipid and resisting obesity. The structural formula of the cryptotanshinone derivative is a novel cryptotanshinone derivative prepared by the inventor for the first time. Researches show that the cryptotanshinone derivative can effectively inhibit adipogenesis, has good safety and better lipid-lowering activity, and is expected to be developed into a novel lipid-lowering obesity-resisting drug.
Inventors:
LIU PEIQING (CN)
YIN SHENG (CN)
LUO SIYUAN (CN)
PAN WENJIE (CN)
YIN SHENG (CN)
LUO SIYUAN (CN)
PAN WENJIE (CN)
Application Number:
PCT/CN2022/097739
Publication Date:
December 15, 2022
Filing Date:
June 08, 2022
Export Citation:
Assignee:
GUANGZHOU SYSU NANSHA SCIENCE & TECH INNOVATION PARK LTD CO (CN)
International Classes:
C07C49/755; A61K31/122; A61P3/04; A61P3/06; C07C45/61
Foreign References:
| CN113402372A | 2021-09-17 | |||
| CN102603861A | 2012-07-25 | |||
| CN106798737A | 2017-06-06 |
Other References:
PING XIAOFAN , YONG GUO , HUA ZHU , YING XUE , DAIQIAN XIE: "Theoretical Study on the Structure Transformations of Cryptotanshinone and Tanshinone I with Hydrion or Hydroxide Ion", JOURNAL OF THEORETICAL AND COMPUTATIONAL CHEMISTRY, vol. 8, no. 2, 31 December 2009 (2009-12-31), US , pages 204 - 213, XP009541822, ISSN: 0219-6336, DOI: 10.1142/S0219633609004757
Attorney, Agent or Firm:
GUANGZHOU NUOFENG INTELLECTUAL PROPERTY AGENT (CN)
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