Α CRYSTAL FORM OF IPI-145 AND PREPARATION METHOD THEREOF

Title:

Α CRYSTAL FORM OF IPI-145 AND PREPARATION METHOD THEREOF

Document Type and Number:

WIPO Patent Application WO/2016/127844

Kind Code:

A1

Abstract:

The present invention relates to an α crystal form of a formula (I) compound used for preparing a leukemia treatment drug and preparation method thereof. The α crystal form provided in the present invention has a better stability, solubility and hygroscopicity comply with pharmaceutical requirements. The α crystal form has a simple preparation method and a low manufacturing cost, and provides a significant value to future optimization and development of the drug.

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Inventors:

CHEN MINHUA (CN)
ZHANG YANFENG (CN)
DIAO XIAOJUAN (CN)
XIA NAN (CN)
ZHANG XIAOYU (CN)

Application Number:

PCT/CN2016/073071

Publication Date:

August 18, 2016

Filing Date:

February 01, 2016

Export Citation:

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Assignee:

CRYSTAL PHARMATECH CO LTD (CN)

International Classes:

C07D473/30; A61K31/52; A61P35/02

Foreign References:

CN103648499A

2014-03-19

Other References: