CRYSTAL FORM OF POTASSIUM-COMPETITIVE ACID BLOCKERS AND PREPARATION METHOD THEREFOR

Title:

CRYSTAL FORM OF POTASSIUM-COMPETITIVE ACID BLOCKERS AND PREPARATION METHOD THEREFOR

Document Type and Number:

WIPO Patent Application WO/2016/074597

Kind Code:

A1

Abstract:

The present invention relates to a crystal form of potassium-competitive acid blockers, that is, 1-[5-(2-fluorophenyl)-1-(pyridine-3-sulfonyl)-1H-pyrrole-3-yl]-N-methyl methylamine fumaric acid salt (which is briefly referred to as a formula I) and a preparation method therefor. An X-ray powder diffraction characteristic peak thereof is shown in FIG. 1. The crystal form that is represented by formula I, provided in the present invention, is stable, has good repeatability, and is suitable for drug development.

Inventors:

TANG HONGWEI (CN)
SUN CHANGAN (CN)
WANG RUIJUN (CN)
YUAN HENGLI (CN)

Application Number:

PCT/CN2015/094120

Publication Date:

May 19, 2016

Filing Date:

November 09, 2015

Export Citation:

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Assignee:

JIANGSU HANSOH PHARMACEUTICAL (CN)

International Classes:

C07D401/12; A61K31/4439; A61P1/04

Foreign References:

CN101300229A

2008-11-05

Other References: