Title:
CULTURE SOLUTION FOR IMPROVING DEVELOPMENTAL QUALITY OF BOVINE IN-VITRO FERTILIZED EMBRYOS AND CLONED EMBRYOS
Document Type and Number:
WIPO Patent Application WO/2021/227225
Kind Code:
A1
Abstract:
Provided is a culture solution for improving the developmental quality of bovine in-vitro fertilized embryos and cloned embryos, the culture solution belonging to the technical field of livestock embryo engineering. The culture solution for improving the developmental quality of bovine in-vitro fertilized embryos and cloned embryos comprises an SOF basic culture medium, and further comprises the following additives: progesterone, vitamin E, L-carnitine, FGF, corticosterone, citrulline, EGF, IGF and LIF. The culture solution for improving the developmental quality of bovine in-vitro fertilized embryos and cloned embryos can effectively improve the developmental rate and developmental quality of bovine in-vitro fertilized embryos and somatic cell cloned embryos.
Inventors:
ZHANG JINGCHENG (CN)
HUANG YUEMENG (CN)
ZHANG MIN (CN)
WANG DEBAO (CN)
WANG YONG (CN)
ZHANG YONG (CN)
HUANG YUEMENG (CN)
ZHANG MIN (CN)
WANG DEBAO (CN)
WANG YONG (CN)
ZHANG YONG (CN)
Application Number:
PCT/CN2020/100821
Publication Date:
November 18, 2021
Filing Date:
July 08, 2020
Export Citation:
Assignee:
UNIV NORTHWEST A&F (CN)
International Classes:
C12N5/073
Domestic Patent References:
| WO2000038583A1 | 2000-07-06 |
Foreign References:
| CN110305836A | 2019-10-08 | |||
| CN109628382A | 2019-04-16 |
Other References:
ZHOU RUI-NIAN,LI RUI-WEN: "The Effect of Vitamin E on the Apoptosis and Development of Human Embryos in Vitro", CHINESE JOURNAL OF FAMILY PLANNING & GYNECOTOKOLOGY, vol. 3, no. 6, 25 December 2010 (2010-12-25), pages 34 - 36+39, XP055867454, ISSN: 1674-4020, DOI: 10.3969/j.issn.1674-4020.2010.06.009
B.C. REGGIO, J.W. LYNN, R.A. GODKE: "The effect of progesterone on the development of IVF-derived bovine embryos cultured in a semi-defined culture medium", THERIOGENOLOGY, vol. 47, no. 1, 1 January 1997 (1997-01-01), US , pages 284, XP009531822, ISSN: 0093-691X, DOI: 10.1016/S0093-691X(97)82411-9
LI NAN;LIN ZHONG: "In Vitro Embryo Culture Is the Core of Embryo Engineering Technology", CHINESE JOURNAL OF TISSUE ENGINEERING RESEARCH, vol. 23, no. 29, 18 July 2019 (2019-07-18), pages 4735 - 4742, XP055867464, ISSN: 2095-4344, DOI: 10.3969/j.issn.2095-4344.1781
B.C. REGGIO, J.W. LYNN, R.A. GODKE: "The effect of progesterone on the development of IVF-derived bovine embryos cultured in a semi-defined culture medium", THERIOGENOLOGY, vol. 47, no. 1, 1 January 1997 (1997-01-01), US , pages 284, XP009531822, ISSN: 0093-691X, DOI: 10.1016/S0093-691X(97)82411-9
LI NAN;LIN ZHONG: "In Vitro Embryo Culture Is the Core of Embryo Engineering Technology", CHINESE JOURNAL OF TISSUE ENGINEERING RESEARCH, vol. 23, no. 29, 18 July 2019 (2019-07-18), pages 4735 - 4742, XP055867464, ISSN: 2095-4344, DOI: 10.3969/j.issn.2095-4344.1781
Attorney, Agent or Firm:
MUDA INTELLECTUAL PROPERTY FIRM (CN)
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