CYANOPYRIDINE DERIVATIVE AND MEDICINAL USE THEREOF

WIPO Patent Application WO/2008/053812

A1

Although several substances inhibiting Aurora kinase 2 have been reported, there has never been found out hitherto one having a sufficient biological activity in treating diseases. Thus, it is intended to provide an Aurora kinase 2 inhibitor which is useful in treating cell proliferative diseases typified by cancer. It is found out that a cyanopyridine compound represented by the following general formula (I), its pharmaceutically acceptable salt or a hydrate, a water adduct or a solvate of the same has a potent carcinostatic effect, thereby completing the invention.

MORIOKA MASAHIKO (JP)
IKEGAMI HIROSHI (JP)
SAKIYAMA MAKOTO (JP)
OOIKE SHINSUKE (JP)
HAYASHI MASAYUKI (JP)
FUJINO YASUHIRO (JP)
ABE DAISUKE (JP)
TOMOZANE HIDEO (JP)

PCT/JP2007/070950

May 08, 2008

October 26, 2007

Click for automatic bibliography generation  

MITSUBISHI TANABE PHARMA CORP (JP)
MORIOKA MASAHIKO (JP)
IKEGAMI HIROSHI (JP)
SAKIYAMA MAKOTO (JP)
OOIKE SHINSUKE (JP)
HAYASHI MASAYUKI (JP)
FUJINO YASUHIRO (JP)
ABE DAISUKE (JP)
TOMOZANE HIDEO (JP)

C07D401/12; A61K31/435; A61K31/4439; A61K31/444; A61K31/4545; A61K31/496; A61K31/497; A61K31/506; A61K31/5377; A61P35/00; A61P43/00; C07D401/14; C07D405/14; C07D409/14; C07D495/04

WO2006082392A1	2006-08-10
WO2002066461A1	2002-08-29
WO2006118231A1	2006-11-09

TAKASHIMA, Hajime (1-1 Fushimimachi 4-chome, Chuo-ku, Osaka-sh, Osaka 44, JP)

View/Download PDF      PDF Help

Previous Patent: METHOD FOR PRODUCING OLEFIN

Next Patent: SEMICONDUCTOR CERAMIC COMPOSITION AND PROCESS FOR PRODUCING THE SAME