Title:
CYCLIC DIPEPTIDE-CONTAINING COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2015/194035
Kind Code:
A1
Abstract:
Disclosed is a cyclic dipeptide-containing composition comprising specific amounts of: tyrosine-containing cyclic dipeptides selected from the group consisting of cyclotryptophanyltyrosine, cycloseryltyrosine, cycloprolyltyrosine, cyclotyrosylglycine, cyclotyrosyltyrosine, cyclophenylalanyltyrosine, cycloleucyltyrosine, cyclolysyltyrosine, cyclohistidyltyrosine, cycloalanyltyrosine, cycloglutamyltyrosine, cyclovalyltyrosine, cycloisoleucyltyrosine, cyclothreonyltyrosine, cycloaspartyltyrosine, cycloasparaginyltyrosine, cycloglutaminyltyrosine, cycloarginyltyrosine, and cyclomethionyltyrosine; or salts thereof. This cyclic dipeptide-containing composition has an excellent uric acid level lowering effect, and is useful for, for example, the prophylaxis or treatment of hyperuricemia, gout, etc.
Inventors:
SUZUKI TOSHIHIDE
FUKIZAWA SHINYA
BEPPU YOSHINORI
WATANABE HIROSHI
FUKIZAWA SHINYA
BEPPU YOSHINORI
WATANABE HIROSHI
Application Number:
PCT/JP2014/066425
Publication Date:
December 23, 2015
Filing Date:
June 20, 2014
Export Citation:
Assignee:
SUNTORY HOLDINGS LTD (JP)
International Classes:
C07K5/12; C07D241/08; C07K5/06; A23G1/00; A23G1/30; A23L1/305; A23L2/00
Domestic Patent References:
| WO2009093141A2 | 2009-07-30 |
Foreign References:
| JP2013531688A | 2013-08-08 | |||
| JP2013053115A | 2013-03-21 | |||
| JP2006111541A | 2006-04-27 |
Other References:
PRASAD, C. ET AL.: "Could dietary proteins serve as cyclo(His-Pro) precursors?", NEUROPEPTIDES, vol. 19, no. l, May 1991 (1991-05-01), pages 17 - 21, XP026324411, ISSN: 0143-4179
NONGONIERMA, A. B. ET AL.: "Tryptophan- containing milk protein-derived dipeptides inhibit xanthine oxidase", PEPTIDES, vol. 37, no. 2, 13 August 2012 (2012-08-13), pages 263 - 272, XP055244800, ISSN: 0196-9781
NONGONIERMA, A. B. ET AL.: "Tryptophan- containing milk protein-derived dipeptides inhibit xanthine oxidase", PEPTIDES, vol. 37, no. 2, 13 August 2012 (2012-08-13), pages 263 - 272, XP055244800, ISSN: 0196-9781
Attorney, Agent or Firm:
HOSODA, YOSHINORI (JP)
Yoshinori Hosoda (JP)
Yoshinori Hosoda (JP)
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