CYCLOSPORIN CONJUGATES - UCL BUSINESS PLC

Title:

CYCLOSPORIN CONJUGATES

Document Type and Number:

WIPO Patent Application WO/2011/010084

Kind Code:

A8

Abstract:

A conjugate which comprises a cyclosporin moiety of formula (I) linked to one or more mitochondrial targeting groups, or a pharmaceutically acceptable salt thereof: wherein: A represents or, B represents methyl or ethyl, one Of R1 and R1 represents hydrogen and the other represents methyl, R2 represents ethyl or isopropyl, R3 represents hydrogen or methyl, and R4 represents -CH2CH(CH3)CH3, -CH2CH(CH3)CH2CH3, -CH(CH3)CH3 or -CH(CH3)CH2CH3.

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Inventors:

SELWOOD DAVID (GB)
CROMPTON MARTIN (GB)

Application Number:

PCT/GB2010/001369

Publication Date:

March 29, 2012

Filing Date:

July 19, 2010

Export Citation:

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Assignee:

UCL BUSINESS PLC (GB)
SELWOOD DAVID (GB)
CROMPTON MARTIN (GB)

International Classes:

A61K47/48; A61P9/10; A61P25/28

Attorney, Agent or Firm:

SRINIVASAN, Ravi Chandran et al. (14 South SquareGray's Inn, London WC1R 5LX, GB)

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