DEVICE FOR SUPPRESSING INFLAMMATION AND HYPERIMMUNITY, AND METHOD FOR SUPPRESSING INFLAMMATION AND HYPERIMMUNITY

Title:

DEVICE FOR SUPPRESSING INFLAMMATION AND HYPERIMMUNITY, AND METHOD FOR SUPPRESSING INFLAMMATION AND HYPERIMMUNITY

Document Type and Number:

WIPO Patent Application WO/2017/065239

Kind Code:

A1

Abstract:

Provided is a new means for suppressing inflammation or suppressing inflammatory cytokine production. Provided is a device in which a weak pulse current is passed through a living body or living tissue to suppress inflammation in the living body or the living tissue. This device is provided with a power supply means, and a current control means for receiving a supply of power to intermittently apply a direct current at prescribed intervals, and is configured such that the current control means includes a pulse width modulation control means, and the pulse width modulation control means generates a pulse wave that is a rectangular wave, and in which the time indicating a peak value for rising in one cycle of the pulse wave ("pulse duration") is at least 0.1 millisecond, the peak value is 1.0-20 V, inclusive, and the duty ratio of the pulse wave is at least 5.5%.

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Inventors:

KAI HIROFUMI (JP)
SHUTO TSUYOSHI (JP)
SUICO MARY ANN SOTEN (JP)
ARAKI EIICHI (JP)
KONDO TATSUYA (JP)

Application Number:

PCT/JP2016/080443

Publication Date:

April 20, 2017

Filing Date:

October 13, 2016

Export Citation:

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Assignee:

NAT UNIV CORP KUMAMOTO UNIV (JP)

International Classes:

A61N1/32

Domestic Patent References:

WO2003080179A1

2003-10-02

Foreign References:

JPH08131560A	1996-05-28
JP2008525102A	2008-07-17
US6535767B1	2003-03-18

Other References:

RYOSUKE FUKUDA ET AL.: "Mild Electrical Stimulation at 0.1-ms Pulse Width Induces p53 Protein Phosphorylation and G2 Arrest in Human Epithelial Cells", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 288, 18 April 2013 (2013-04-18), pages 16117 - 16126, XP002727608
See also references of EP 3363494A4

Attorney, Agent or Firm:

OSAWA Kenichi (JP)

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