Title:
DRUG FOR TREATING SKIN DISEASE
Document Type and Number:
WIPO Patent Application WO/2006/035760
Kind Code:
A1
Abstract:
Disclosed is an urea compound having a structure represented by the general formula [1] below which has a new pharmacological effect. The urea compound having the structure represented by the general formula [1] below or a salt thereof has an excellent curative effect on skin diseases. In the formula below, A represents -(NR4)-, -(CR5R6)- or -O-; B represents an alkylene or alkenylene group; R1, R2, R4, R5 and R6 respectively represent a hydrogen atom, an alkyl group, an alkenyl group, an adamantylalkyl group or the like; R3 represents an aryl group or an unsaturated heterocyclic ring; and X represents an oxygen atom or a sulfur atom.
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Inventors:
AONO HIROYUKI (JP)
HORIUCHI MASATO (JP)
TSUJI FUMIO (JP)
MURAI MASAAKI (JP)
HORIUCHI MASATO (JP)
TSUJI FUMIO (JP)
MURAI MASAAKI (JP)
Application Number:
PCT/JP2005/017720
Publication Date:
April 06, 2006
Filing Date:
September 27, 2005
Export Citation:
Assignee:
SANTEN PHARMACEUTICAL CO LTD (JP)
AONO HIROYUKI (JP)
HORIUCHI MASATO (JP)
TSUJI FUMIO (JP)
MURAI MASAAKI (JP)
AONO HIROYUKI (JP)
HORIUCHI MASATO (JP)
TSUJI FUMIO (JP)
MURAI MASAAKI (JP)
International Classes:
A61K31/4409; A61K9/00; A61P17/00; A61P17/04; A61P17/06; A61P17/08; A61P29/00; C07D213/40
Domestic Patent References:
| WO2002098869A2 | 2002-12-12 | |||
| WO2004048317A1 | 2004-06-10 | |||
| WO2003077847A2 | 2003-09-25 |
Foreign References:
| JP2002053555A | 2002-02-19 | |||
| JPH07165555A | 1995-06-27 | |||
| JP2003192659A | 2003-07-09 |
Other References:
DATABASE PUBMED [online] BENOIT S. ET AL: "Treatment of recalcitrant pustular psoriasis with infliximab: effective reduction of chemokine expression", XP002993887, accession no. NCBI Database accession no. 15149518
DATABASE PUBMED [online] VINCEK V. ET AL: "Infliximab monotherapy in psoriasis: a case of rapid clinical and histological response", XP002993888, accession no. NCBI Database accession no. 15090021
DATABASE PUBMED [online] VINCEK V. ET AL: "Infliximab monotherapy in psoriasis: a case of rapid clinical and histological response", XP002993888, accession no. NCBI Database accession no. 15090021
Attorney, Agent or Firm:
Hibi, Norihiko c/o KISHIMOTO & CO. (3rd Floor Inaba Building, 13-18,
Nishishinsaibashi 1-chome, Chuo-k, Osaka-shi Osaka, JP)
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