スルホンアミド誘導体

Japanese Patent JP2009507904

A

The invention relates to sulphonamide derivatives of formula (I), where RC is selected from a group consisting of dialkylamino, NO2, CN, aminocarbonyl, monoalkylaminocarbonyl, dialkylaminocarbonyl, alkanoyl, oxazol-2-yl, oxazolylaminocarbonyl, aryl, aroyl, aryl-CH(OH)-, arylaminocarbonyl, furanyl, where the aryl, aroyl and furanyl moieties may be substituted, guanidinyl-(CH2)z-N(R')-, Het-(CH2)z-N(R')-, Het-CO-N(R')-, Het-CH(OH)- and Het-CO-, where Het is an optionally substituted 4-6-membered heterocyclic ring containing one or more heteroatoms sleeted from N, S and O, R' is hydrogen or alkyl, and z is an integer 1 to 5; RA is a group of formula (A), (B), (C) or (D) as defined in the claims; and RB is hydrogen, alkyl, alkanoyl, hydroxyalkyl, alkoxyalkyl, alkoxycarbonyl, alkoxycarbonylalkyl, aminoalkyl, mono- or dialkylaminoalkyl or Het-alkyl, where Het is as defined above. The invention also relates to the use of derivatives of formula (I) as inhibitors for collagen receptor integrins and a process for preparing sulphonamides of formula (II).

JPH04230256	PRODUCTION OF AMINOANTHRAQUINONE DERIVATIVE
JP2001506596	INDUSTRIAL APPLICABILITY The use of benzamide aldehyde and cysteine protease as an inhibitor.
WO/2008/126731	ARYL DERIVATIVES

Heino, Iruki
Johnson, mark
Capile, Yarmo
Maruameki, Anne
Nironen, Tongmi
Oyara, Marika
Penticainen, Ori
Pyflavis, Maruyo
Nissinen, Lisa

JP2008530557A

February 26, 2009

September 15, 2006

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BIOTY THERAPIES CORPORATION

C07C311/21; A61K31/18; A61K31/401; A61K31/4166; A61K31/42; A61K31/4409; A61K31/5375; A61P7/02; A61P9/00; A61P29/00; A61P35/00; A61P43/00; C07C303/38; C07C311/51; C07C311/53; C07D207/34; C07D207/416; C07D213/50; C07D233/38; C07D261/08; C07D261/14; C07D261/18; C07D263/32; C07D295/192; C07C

Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Ryotaro Takei

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