Title:
ENHANCED IMMUNE CELLS USING DUAL SHRNA AND COMPOSITION INCLUDING THE SAME
Document Type and Number:
WIPO Patent Application WO/2019/138354
Kind Code:
A1
Abstract:
The present disclosure is broadly concerned with the field of cancer immunotherapy. For example, the present invention generally relates to an immune cell comprising a genetically engineered antigen receptor that specifically binds to a target antigen and a genetic disruption agent that reduces or is capable of reducing the expression in the immune cell of a gene that weakens the function of the immune cell.
More Like This:
| WO/1999/003890 | NOVEL PEPTIDES AND POLYPEPTIDES USEFUL FOR REGENERATING THE NERVOUS SYSTEM |
| JP7075678 | Peptide ligase and its use |
| JP2022509942 | Anti-NKG2A antibody and its use |
Inventors:
KIM CHAN HYUK (KR)
LEE YOUNG-HO (KR)
LEE YUJEAN (KR)
LEE HYEONGJI (KR)
LEE SANG HOON (KR)
LEE YOUNG-HO (KR)
LEE YUJEAN (KR)
LEE HYEONGJI (KR)
LEE SANG HOON (KR)
Application Number:
PCT/IB2019/050194
Publication Date:
July 18, 2019
Filing Date:
January 10, 2019
Export Citation:
Assignee:
CUROCELL INC (KR)
KOREA ADVANCED INST SCI & TECH (KR)
KOREA ADVANCED INST SCI & TECH (KR)
International Classes:
C12N15/63; A61K35/17; C07K14/725; C07K16/30; C12N5/0783; C12N15/113
Domestic Patent References:
| WO2015142675A2 | 2015-09-24 | |||
| WO2018012895A1 | 2018-01-18 | |||
| WO2016069282A1 | 2016-05-06 |
Foreign References:
| US20160311917A1 | 2016-10-27 | |||
| US20140227237A1 | 2014-08-14 | |||
| US20140219975A1 | 2014-08-07 | |||
| US6352694B1 | 2002-03-05 | |||
| US6534055B1 | 2003-03-18 | |||
| US6905680B2 | 2005-06-14 | |||
| US6692964B1 | 2004-02-17 | |||
| US5858358A | 1999-01-12 | |||
| US6887466B2 | 2005-05-03 | |||
| US6905681B1 | 2005-06-14 | |||
| US7144575B2 | 2006-12-05 | |||
| US7067318B2 | 2006-06-27 | |||
| US7172869B2 | 2007-02-06 | |||
| US7232566B2 | 2007-06-19 | |||
| US7175843B2 | 2007-02-13 | |||
| US5883223A | 1999-03-16 | |||
| US6905874B2 | 2005-06-14 | |||
| US6797514B2 | 2004-09-28 | |||
| US6867041B2 | 2005-03-15 | |||
| US20060121005A1 | 2006-06-08 | |||
| US4690915A | 1987-09-01 |
Other References:
SAMBROOK ET AL.: "Molecular Cloning: A Laboratory Manual", 2012
WANJUN CHEN, JEM, 2003
MILONE ET AL., MOLECULAR THERAPY, vol. 17, no. 8, 2009, pages 1453 - 1464
"Monoclonal Antibodies: Methods and Protocols", vol. 1, 2, 2010
"Molecular Biology of the Cell", 2014
ELBASHIR SM ET AL., NATURE, vol. 411, 2001, pages 494 - 498
SHOHEI HORI, SCIENCE, 2003
DAT Q. TRAN, BLOOD, 2007
See also references of EP 3737765A4
WANJUN CHEN, JEM, 2003
MILONE ET AL., MOLECULAR THERAPY, vol. 17, no. 8, 2009, pages 1453 - 1464
"Monoclonal Antibodies: Methods and Protocols", vol. 1, 2, 2010
"Molecular Biology of the Cell", 2014
ELBASHIR SM ET AL., NATURE, vol. 411, 2001, pages 494 - 498
SHOHEI HORI, SCIENCE, 2003
DAT Q. TRAN, BLOOD, 2007
See also references of EP 3737765A4
Attorney, Agent or Firm:
LEE & KO IP (KR)
Download PDF: